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Evaluation of the therapeutic effect on consumption of Opuntia ficus-indica Haw (Cactaceae)

    Elaine Cristina Birssi

    Paranaense University (UNIPAR), Pharmacy Department, Praça Mascarenhas de Moraes, 4282, Centro, CEP 87502-210, Umuarama, PR, Brazil.

    http://lattes.cnpq.br/3469437628808389.

    Possui graduação em farmácia pelo Centro Universitário de Maringá (2010); Especialista em Farmacologia com ênfase em Prescrição farmacêutica - Universidade Estadual de Maringá (UEM, 2017); Especialista em Biotecnologia e Bioprocessos - Universidade Estadual de Maringá (UEM, 2017); Especialista em Bases Morfofuncionais do corpo humano - Universidade Estadual de Maringá (UEM 2018); Especialista em Farmácia Clínica e Farmácia Hospitalar com ênfase em prescrição farmacêutica (UNIPAR, 2018); Especialista em Controle de Infecção Relacionado à Assistência à Saúde - Universidade Estadual de Londrina (UEL, 2019); Mestrado em Andamento em Infecção Hospitalar - Programa de Pós-Graduação em Biociências e Fisiopatologia da Universidade de Estadual de Maringá (UEM, 2019). Atualmente Farmacêutica Clínica no hospital Bom Samaritano de Maringá. Experiências profissionais na área de farmácia comercial, Farmácia Básica do SUS (Município de Ibema), Laboratório de análises clínicas, Professora do curso técnico de Farmácia, Farmácia Hospitalar/Farmácia Clínica.

    Guilherme Donadel

    Paranaense University, Laboratory of preclinical research of natural products, Praça Mascarenhas de Moraes, 4282, Centro, CEP 87502-210, Umuarama, PR, Brazil.

    http://lattes.cnpq.br/6229413469325907.

    Veterinary Doctor, graduated from Universidade Paranaense (UNIPAR) in 2019, student of the master's program in animal science and bioactive products, scholarship (PROSUP/CAPES), UNIPAR.

    Débora Gafuri Teixeira

    Ingá University Center (UNINGÁ), Department of Health Sciences, PR 317 n° 6114, Ingá, CEP 87035-510, Maringá, PR, Brazil.

    Renan Almeida de Jesus

    Faculty of Health Sciences of Unaí (Facisa), Veterinary clinic, Rua Manoel P. Santana, 52, Capim Branco, CEP: 38610-000, Unaí, MG, Brazil.

    http://lattes.cnpq.br/2736983302725906.

    Graduated in Pharmacy from Universidade Paranaense (2009), Specialization in Homeopathic Pharmacy from the Brazilian Association of Homeopathic Pharmacists (2011), Specialization in Applied Pharmacology and Therapeutics from Universidade Paranaense (2014), Specialization in Psychology and Sexuality from Universidade de Araraquara ( 2018) and Master in Biotechnology Applied to Agriculture from Universidade Paranaense (2018) working in the line of research of characterization and biological activities of natural products. He was the Technical Responsible for the Homeopathic Laboratory at Nutriphós Indústria e Comércio de Veterinary Products between 2010 and 2018. He is currently a professor at the Faculty of Health Sciences of Unaí (FACISA) and an Acupuncturist. He has experience in the field of Pharmacy, with an emphasis on Homeopathy, Pharmacognosy, Phytochemistry, Pharmacology and Integrative Practices.

    Juliana Cogo

    Cesumar University (UNICESUMAR), Av. Guedner, 1610, Jardim Aclimação, CEP 87050-900, Maringá, PR, Brazil.

    http://lattes.cnpq.br/8330995716331248.

    Graduated in Pharmacy from Universidade Paranaense (2009), Master's degree in Pharmaceutical Sciences from Universidade Estadual de Maringá (2012), where his line of research is the area of ​​Biologically Active Natural Products, working mainly on the following topics: Medicinal plants, isolation and purification of secondary metabolites, chromatography, protozoa, Trypanosoma cruzi and Leishmania amazonensis. She did her PhD in Pharmaceutical Sciences also at the State University of Maringá (2016), where she held a sandwich doctorate at the GlaxoSmithKline laboratories in Tres Cantos (Spain; 2013-2014) and worked as a researcher at the Foundation for Institutional Support for Scientific and Technological Development? FAI?UFSCar, in which she carried out in vitro and in vivo investigation of semi-synthetic derivatives for the treatment of Chagas disease, human African trypanosomiasis and leishmaniasis.

    Mariana Dalmagro

    Paranaense University, Laboratory of preclinical research of natural products, Praça Mascarenhas de Moraes, 4282, Centro, CEP 87502-210, Umuarama, PR, Brazil.

    http://lattes.cnpq.br/2985414963337701.

    Graduated from the Pharmacy Course at Universidade Paranaense UNIPAR (2017-2020) where she received the title of Best Student of the Year. She participated in the External Program of Scientific Initiation Scholarship - PEBIC/PIBITI/CNPQ (2017-2019). She acted as monitor of the discipline of Human Anatomy (2018) and Pharmacology applied to health (2020). Currently, a master's student in Biotechnology applied to agriculture (UNIPAR) and a graduate student in Specialization in Advanced Aesthetics: Non-surgical Invasive Procedures (UNIPAR) and a graduate student in Specialization in Pharmacology and Drug Interactions (UNINTER).

    Odair Alberton

    Paranaense University, Laboratory of preclinical research of natural products, Praça Mascarenhas de Moraes, 4282, Centro, CEP 87502-210, Umuarama, PR, Brazil.

    http://lattes.cnpq.br/5399268772894807.

    Graduated in Agronomy from the State University of Santa Catarina-UDESC (2001), Master in Microbiology from the State University of Londrina-UEL (2003), Ph.D. in "Production Ecology and Resource Conservation" at Wageningen University - Netherlands, in April 2008 , being recognized as a doctorate in agronomy by the State University of Londrina-UEL (2009) and a post-doctoral internship at Embrapa-Soja in 2009 with a DTI-CNPq scholarship. Has experience in Agronomy, with an emphasis on Soil Microbiology and Biochemistry, acting on the following topics: soil management systems, soil biology and microbiology, mycorrhizaes, Interaction of plants x micro-organisms, symbioses, biological nitrogen fixation, medicinal plants and meta-analyses. Member of the collegiate and supervisor of the Graduate Program (Masters and Doctorate) in Biotechnology Applied to Agriculture at UNIPAR (2010-2018) and coordinator, member of the collegiate and supervisor of the program (2020 to date). Member of the collegiate and advisor in the Graduate Program Stricto Sensu Professional Master's in Medicinal Plants and Herbal Medicines in Primary Care at UNIPAR (2018 to date). He completed the supervision of 14 master's dissertations, a doctoral thesis. He is currently a Professor in the undergraduate courses in business administration (statistics), agronomic engineering (TCC) and Distance Education EaD (disciplines of: statistics, environmental microbiology and geology). Coordinator of the Lato Sensu postgraduate course: "Microbiology and Microbiological Quality Control" at Universidade Paranaense - UNIPAR. Member of CIBio-UNIPAR/CTNBio (2010-2018 and 2020 to date). Reviewer of more than 45 journals and published 95 scientific articles and 3 books since 2005. Ad hoc consultant for projects and grants from Fundação Araucária-PR, Pernambuco Foundation for Science and Technology (FACEPE), CAPES and CNPq. ORCID iD: https://orcid.org/0000-0002-4819-6669.

    Daniela de Cassia Faglioni Boleta-Ceranto

    Paranaense University, Laboratory of preclinical research of natural products, Praça Mascarenhas de Moraes, 4282, Centro, CEP 87502-210, Umuarama, PR, Brazil.

    Graduated in Dentistry from Universidade Paranaense (1998), Master's in Dentistry Oral Physiology from Universidade Estadual de Campinas (2002) and Ph.D. Specialization in Acupuncture recognized by the Federal Council of Dentistry. Executive MAB in Business Strategies. She is currently a professor at the Universidade Paranaense campus, Umuarama, in the courses of Dentistry and Professional Masters in Medicinal Plants and Herbal Medicines in Primary Care. She has teaching experience in the disciplines of Human Physiology, Anatomy-Physiology, Oral Diagnosis and Research Methodology, in the field of Dentistry. In the area of ​​Oral Diagnosis, she coordinates projects with the objective of making the early diagnosis of oral cancer and cancerizable lesions. Member of the Human Research Ethics Committee. Member of the Board of Dentistry Courses and Professional Master's Degree in Medicinal Plants at Unipar. Coordinator of the Auriculotherapy Update Course at Unipar. https://orcid.org/0000-0002-6654-951X

    Emerson Luiz Botelho Lourenço

    Paranaense University, Laboratory of preclinical research of natural products, Praça Mascarenhas de Moraes, 4282, Centro, CEP 87502-210, Umuarama, PR, Brazil.

    Giuliana Zardeto

    Paranaense University, Laboratory of preclinical research of natural products, Praça Mascarenhas de Moraes, 4282, Centro, CEP 87502-210, Umuarama, PR, Brazil.

    Graduated in General Pharmacy from Universidade Paranaense (UNIPAR)(2011), with Qualification in Homeopathic Pharmacy. He has a Master's Degree in Pharmaceutical Sciences from the State University of Maringá (UEM)(2016), concentration area: Biologically Active Natural and Synthetic Products and a Doctorate from the Postgraduate Program in Biotechnology Applied to Agriculture (UNIPAR)(2019), concentration area: Development of Natural Products. He is currently Full Professor at Universidade Paranaense (UNIPAR), teaching in Pharmacy and Medicine courses and collaborating professor in the Professional Master's Degree in Medicinal Plants and Herbal Medicines in Primary Care (2020-current), working in the area of ​​Biologically Active Natural Products, mainly in the following topics: Medicinal Plants, Herbal Medicines in primary care, chemistry of natural products, extraction of essential oils, crude extracts, fractions and isolation of secondary metabolites. She is the coordinator of the supervised internships of the undergraduate course in Pharmacy-in-person mode, Umuarama / PR. She is coordinator of specializations in Clinical Pharmacy and Hospital Pharmacy with an emphasis on Pharmaceutical Prescription, Clinical and Toxicological Analysis, Medicinal Plants and Herbal Medicines and Advanced Aesthetics: Non-surgical Invasive Procedures, reviewer of periodicals in the area of ​​Health Sciences and since 2017 is a Titular Member of Brazilian Association of Phytotherapy (ABFIT).

Keywords

Abstract

Opuntia ficus-indica Haw (Cactaceae) is a xerophilous plant, developing in arid and semi-arid climates popularly known as prickly pear, fig tree or nopal. This study aimed to determine the beneficial effects of phytochemicals present in Opuntia ficus-indica. To this end, a literature review was carried out in the Google Scholar® and PubMed databases using the health descriptors: Opuntia ficus-indica, prickly pear and nopal, until 2020. As an inclusion criterion, the articles were analyzed based on the quality of the hypothesis / objective description; quality of the description of the outcome to be studied; characterization of the included sample; quality of the description and discussion of the main photochemical compounds found in Opuntia ficus-indica related to the benefits for human health; quality of the description of the study's main findings. Cladodes are the most used part of the plant, where most of the important beneficial properties that are used for human health and disease prevention are concentrated. In view of what is available in the literature, it is concluded that it is a plant that has not been explored much, therefore, more studies are needed for new discoveries to be made about the biological activities of the plant under study.

References

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Author(s)

  • Elaine Cristina Birssi
    Paranaense University (UNIPAR), Pharmacy Department, Praça Mascarenhas de Moraes, 4282, Centro, CEP 87502-210, Umuarama, PR, Brazil.
  • Guilherme Donadel
    Paranaense University, Laboratory of preclinical research of natural products, Praça Mascarenhas de Moraes, 4282, Centro, CEP 87502-210, Umuarama, PR, Brazil.
  • Débora Gafuri Teixeira
    Ingá University Center (UNINGÁ), Department of Health Sciences, PR 317 n° 6114, Ingá, CEP 87035-510, Maringá, PR, Brazil.
  • Renan Almeida de Jesus
    Faculty of Health Sciences of Unaí (Facisa), Veterinary clinic, Rua Manoel P. Santana, 52, Capim Branco, CEP: 38610-000, Unaí, MG, Brazil.
  • Juliana Cogo
    Cesumar University (UNICESUMAR), Av. Guedner, 1610, Jardim Aclimação, CEP 87050-900, Maringá, PR, Brazil.
  • Mariana Dalmagro
    Paranaense University, Laboratory of preclinical research of natural products, Praça Mascarenhas de Moraes, 4282, Centro, CEP 87502-210, Umuarama, PR, Brazil.
  • Odair Alberton
    Paranaense University, Laboratory of preclinical research of natural products, Praça Mascarenhas de Moraes, 4282, Centro, CEP 87502-210, Umuarama, PR, Brazil.
  • Daniela de Cassia Faglioni Boleta-Ceranto
    Paranaense University, Laboratory of preclinical research of natural products, Praça Mascarenhas de Moraes, 4282, Centro, CEP 87502-210, Umuarama, PR, Brazil.
  • Emerson Luiz Botelho Lourenço
    Paranaense University, Laboratory of preclinical research of natural products, Praça Mascarenhas de Moraes, 4282, Centro, CEP 87502-210, Umuarama, PR, Brazil.
  • Giuliana Zardeto
    Paranaense University, Laboratory of preclinical research of natural products, Praça Mascarenhas de Moraes, 4282, Centro, CEP 87502-210, Umuarama, PR, Brazil.

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How to Cite

1.
Evaluation of the therapeutic effect on consumption of Opuntia ficus-indica Haw (Cactaceae). Rev Fitos [Internet]. 2022 Mar. 31 [cited 2025 Apr. 8];16(1):77-82. Available from: https://revistafitos.far.fiocruz.br/index.php/revista-fitos/article/view/1233
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