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Morinda citrifolia: fatos e riscos sobre o uso do noni | Revista Fitos

Morinda citrifolia: fatos e riscos sobre o uso do noni

Andreia Freire Barbosa
Isabelly Cristina de Matos Costa
Silvana Zucolotto Langassner
Raquel Brandt Giordani
OrcID

Keywords

Morinda citrifolia. Fitoterapia. Atividade farmacológica. Toxicidade

Abstract

Morinda citrifolia L. (Rubiaceae), popularmente conhecida como noni, é amplamente utilizada, na Polinésia e no Havaí, para tratamento de diversas patologias, como: dislipidemia, diabetes, câncer, hipertensão, cicatrização, dentre outras.  Atualmente, observa-se também o uso exacerbado no Brasil, especialmente na região Nordeste, onde a planta se adaptou bem. Porém, ainda não há certeza da sua eficácia, e muitas pesquisas sobre a ação terapêutica do noni estão em desenvolvimento, embora os resultados sejam bastante controversos. O que torna o noni uma planta diferenciada e que requer atenção especial é seu potencial hepatotóxico. A Agência Nacional de Vigilância Sanitária (ANVISA) fundamenta a sua recomendação de não utilizar o noni, também, com base em relatos de toxicidade em humanos. Este trabalho é uma revisão da literatura, com objetivo de avaliar o potencial terapêutico desta planta de acordo com os estudos já desenvolvidos. Dessa forma, é possível realizar uma análise crítica do uso irracional desta planta e contribuir com a divulgação de possíveis riscos à saúde. 

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Author(s)

  • Andreia Freire Barbosa
    Universidade Federal do Rio Grande do Norte, Centro de Ciências da Saúde, Departamento de Farmácia, Laboratório de Farmacognosia - Rua General Gustavo Cordeiro de Farias, s/n, CEP: 59010-180, Natal, RN, Brazil.
  • Isabelly Cristina de Matos Costa
    Universidade Federal do Rio Grande do Norte, Centro de Ciências da Saúde, Departamento de Farmácia, Laboratório de Farmacognosia - Rua General Gustavo Cordeiro de Farias, s/n, CEP: 59010-180, Natal, RN, Brazil.
  • Silvana Zucolotto Langassner
    Universidade Federal do Rio Grande do Norte, Centro de Ciências da Saúde, Departamento de Farmácia, Laboratório de Farmacognosia - Rua General Gustavo Cordeiro de Farias, s/n, CEP: 59010-180, Natal, RN, Brazil.
  • Raquel Brandt Giordani
    Universidade Federal do Rio Grande do Norte, Centro de Ciências da Saúde, Departamento de Farmácia, Laboratório de Farmacognosia - Rua General Gustavo Cordeiro de Farias, s/n, CEP: 59010-180, Natal, RN, Brazil.
    http://orcid.org/0000-0001-6500-0755

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1.
Morinda citrifolia: fatos e riscos sobre o uso do noni. Rev Fitos [Internet]. 2018 Jan. 9 [cited 2024 Nov. 15];11(2):189-215. Available from: https://revistafitos.far.fiocruz.br/index.php/revista-fitos/article/view/365
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