https://orcid.org/0000-0001-8305-9339
Graduated in Physiotherapy from the University of Vale do Itajaí (2000) and Master and PhD in Pharmacology from the Federal University of Santa Catarina (2006). Has experience in Pharmacology, focusing on Pharmacology of Pain and Inflammation. He is part of the faculty of the University of Vale do Itajaí in the Physiotherapy, Medicine and Biomedicine Course and in the Postgraduate Program in Pharmaceutical Sciences. He recently held a postdoctoral internship at Boston Children's Hospital - Harvard Medical School (USA) under the supervision of Professor Dr. Clifford Woolf. in the area of pain neurobiology.
https://orcid.org/0000-0002-8947-2965
Organic Chemistry from the Federal University of Santa Catarina (1987), a master's degree from the Federal University of Santa Catarina (1991) and a doctorate in Graduate Studies in Chemistry from the Federal University of Santa Catarina (1995). He is currently Rector of the University of Vale do Itajaí (UNIVALI), President of the UNIVALI Foundation and professor / researcher of the Graduate Program (M / D) in Pharmaceutical Sciences of UNIVALI. Develops research projects in collaboration with national and international researchers. He also acts as Network Coordinator RIBIOFAR / CYTED / CNPq and RIBECANCER / CYTED / CNPq. Has experience in Organic Chemistry, focusing on Chemistry, acting on the following subjects: bioactive natural products, synthesis of molecules of biological interest, evaluation of the chemical structure-biological activity relationship. He has over 360 published articles, 50 books and book chapters, and 10 patents. He directed about 50 Dissertations and Theses. He has been a reviewer for over 50 journals and serves as Associate Editor The Scientific World Journal and Pharmaceutical Biology. In 2012, he received the Caspar Stemmer Innovation Award (FAPESC) in the Innovation Protagonist Category (First Place. In 2013, he was nominated as a Finalist of the Santander Student Guide Award (Partnership with the Private Sector), for the project developed in partnership with Eurofarma Pharmaceutical Industry In 2015, was nominated Finalist of the Santander 2015 Award in the Science and Innovation category, with the project entitled "Search for new and effective anticancer agents from the Brazilian biodiversity." In 2017, he received the 1st Merit Commendation. Academic of the Council of Rectors of Brazilian Universities (CRUB), sponsored by CNPq, for the contribution to Brazilian Higher Education In March 2018, he assumed the Presidency of the Foundation and the Rectorate of UNIVALI until 2022.
This work, of partnerships between a Community University and national pharmaceutical companies reports the development of new and effective phytotherapics obtained from the leaves of Aleurites mollucanus (Euphorbiaceae), an exotic species, from Asia, adapted in Brazil. The project, although it has not yet reached the final stage of clinical studies and registration with ANVISA, represents a relevant experience to be analyzed in light of the difficulties and overcomes during the stages that make up the chain of establishment of a new herbal medicine in Brazil. Tablets were developed based on the standardized dry extract of A. moluccanus, on pilot scale, with approval in the stages of non-clinical studies and in the clinical stage-phase I. In addition, formulations such as topical cream and oral suspension were established. The overcoming of challenges related to the standardization of the extract on an industrial scale, under good manufacturing practices (GMP) and the stability aspects of the formulations, the continuity of studies depends on the scenario and consequent market direction. Therefore, this report provides an insight into the setbacks and overcoming experienced by researchers from Brazilian Community University with a focus on research and development of new, effective and safe analgesic and anti-inflammatory herbal medicine.
https://orcid.org/0000-0001-8305-9339
https://orcid.org/0000-0002-8947-2965
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