Potencial terapêutico da camomila (Matricaria chamomilla L., Asteraceae) no manejo da mucosite oral: : revisão integrativa

Emmanuelle de Siqueira Leal Capellini
OrcID
Maria Helena Durães Alves Monteiro
OrcID

    Emmanuelle de Siqueira Leal Capellini

    Fundação Oswaldo Cruz. Instituto de Tecnologia em Fármacos/Farmanguinhos

    OrcID https://orcid.org/0000-0001-8922-4622

    061981314841

    Lattes: Não encontrado.

    Cirurgiã-dentista, servidora pública no Hospital REgional de Taguatinga, Preceptora do Programa de REsidencia em terapia intensiva da SES/FEPECS/DF, intensivista, paliativista, odontologia hospitalar e oncologia.

    Maria Helena Durães Alves Monteiro

    Fundação Oswaldo Cruz. Instituto de Tecnologia em Fármacos/Farmanguinhos

    OrcID https://orcid.org/0000-0001-7434-5544

Palavras-chave

Matricaria chamomilla
Camomila
Estomatite
Mucosite oral
Quimioterapia
Radioterapia

Resumo

O câncer é a doença que mais cresce no mundo, e o seu tratamento é às custas de diversos efeitos colaterais, dentre eles a mucosite oral. A mucosite oral impacta na qualidade de vida, podendo levar a hospitalização. Dentre os tratamentos para a mucosite oral estão a indicação de fitoterápicos para uso tópico e redução da sintomatologia. A Matricaria chamomilla L. Asteraceae, é uma das plantas medicinais mais promissoras para o manejo da mucosite oral, com potencial terapêutico significativo no tratamento desta e de outras afecções orais. Este trabalho tem o objetivo de investigar o potencial terapêutico da camomila (Matricaria chamomilla L. Asteraceae) no manejo da mucosite oral a fim de contribuir para a inovação de uma formulação farmacêutica para aplicação clínica. Foram analisados 48 estudos numa revisão integrativa.  Dentre estes, 70,8% demonstraram que esta planta medicinal possui ação antiinflamatória e com significativa redução na intensidade, severidade e duração das lesões orais. No entanto, os estudos não comprovaram a eficácia na prevenção ou incidência da mucosite oral, e a limitação se dá pela falta de um protocolo embasada e numa formulação farmacêutica padronizada que seja eficaz também no surgimento desta manifestação como efeito colateral a terapia antineoplásica.

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Potencial terapêutico da camomila (Matricaria chamomilla L., Asteraceae) no manejo da mucosite oral: : revisão integrativa. Rev Fitos [Internet]. 7º de março de 2024 [citado 31º de dezembro de 2024];18(Suppl. 3):e1622. Disponível em: https://revistafitos.far.fiocruz.br/index.php/revista-fitos/article/view/1622
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