Potential therapeutic effects of yerba mate (Ilex paraguariensis St. Hil. Aquifoliaceae) consumption for menopausal women: a systematic review

Fábio Tonissi Moroni
Micaela Lemos Reis
Raquel Borges-Moroni
José Fausto de Morais
Nadia Carla Cheik
Elmiro Santos Resende

    Fábio Tonissi Moroni

    Federal University of Uberlândia (UFU), Faculty of Medicine, Department of Internal Medicine. Campus Umuarama, CEP 38408-100, Uberlândia, MG, Brazil.

    Graduated in Veterinary Medicine from the Federal University of Uberlândia (1998) and Administration from the Federal University of Amazonas (2006), Master's in Genetics and Biochemistry from the Federal University of Uberlândia (2001) and PhD in Biological Sciences from the National Institute for Research in the Amazon (2005). ). He is currently an adjunct professor at the Faculty of Medicine of the Federal University of Uberlândia (FAMED / UFU). He has scientific experience in the areas of muscle biophysics and biochemistry, bioassays and epidemiology of human ectoparasites. He also has administrative experience in the area of facility management for biomedical research.

    Micaela Lemos Reis

    Federal University of Uberlândia (UFU), Faculty of Medicine, Department of Internal Medicine. Campus Umuarama, CEP 38408-100, Uberlândia, MG, Brazil

    She is currently a medical student at the Federal University of Uberlândia (UFU). Throughout her academic training, she had experience in scientific initiation research on the potential of plant extracts to inhibit snake venom, epidemiological research with the publication of a corresponding article and activities by the Academic League of Neurology and Neurosurgery (LANNC).

    Raquel Borges-Moroni

    Federal University of Uberlândia (UFU), Institute of Biomedical Sciences, Department of Parasitology. Campus Umuarama, CEP 38405-318, Uberlândia, MG, Brazil

    Degree in Biological Sciences (licence and bachelor's degree) from the Federal University of Uberlândia (UFU), Master's degree in Applied Immunology and Parasitology from the Federal University of Uberlândia and PhD in Entomology from the National Institute for Research in the Amazon (INPA). Professor at the Dept. Parasitology/ICBIM/UFU. Research areas: Parasitology, with emphasis on ectoparasites, Genetics, with emphasis on anopheline genetics.

    José Fausto de Morais

    Federal University of Uberlândia (UFU), Faculty of Mathematics, Campus Santa Monica, CEP 38400-902, Uberlândia, MG, Brazil

    Degree in Biological Sciences (licence and bachelor's degree) from the Federal University of Uberlândia (UFU), Master's degree in Applied Immunology and Parasitology from the Federal University of Uberlândia and PhD in Entomology from the National Institute for Research in the Amazon (INPA). Professor at the Dept. Parasitology/ICBIM/UFU. Research areas: Parasitology, with emphasis on ectoparasites, Genetics, with emphasis on anopheline genetics.

    Nadia Carla Cheik

    Federal University of Uberlândia (UFU), Faculty of Physical Education and Physiotherapy, Physical Education Campus, CEP 38400-678, Uberlândia, MG, Brazil

    He holds a degree in Full Degree in Physical Education from the Federal University of Uberlândia (1999), a master's degree (2002) and a doctorate (2005) in Physiological Sciences from the Federal University of São Carlos. She is currently an adjunct professor 3 at the Federal University of Uberlândia (UFU / FAEFI). She has experience in the area of Human Physiology, with an emphasis on Obesity and Metabolic Syndrome Treatment; Obesity and exercise-induced bronchospasm; Prescription for Special Groups (obese, diabetic, hypertensive, coronary patients) works mainly on the following topics: obesity and associated diseases, exercise physiology, metabolism and nutrition.

    Elmiro Santos Resende

    Federal University of Uberlândia (UFU), Faculty of Medicine, Department of Internal Medicine. Campus Umuarama, CEP 38408-100, Uberlândia, MG, Brazil

    Graduated in Medicine from the Federal University of Uberlândia (1977), with a PhD in Cardiology from the Federal University of São Paulo (1986). He is a Full Professor, since February/2015, at the Department of Internal Medicine - Cardiology Specialty, at the Faculty of Medicine of the Federal University of Uberlândia and a physician in the Cardiology and Intensive Care services of the Hospital de Clínicas of the Federal University of Uberlândia. He is coordinator of the experimental medicine laboratory and clinical research center at the Hospital de Clínicas of the Federal University of Uberlândia (HC-UFU) developing research in atherosclerosis and cardiovascular remodeling, with an emphasis on regenerative processes and cell therapy. He also coordinates the Telehealth sector at HC-UFU and oversees studies in capturing, processing and transmitting cellular electrical signals and telemedicine systems. Rector of the Federal University of Uberlândia, mandate 2012/2016. Leader of the following research groups - CNPQ: Cardioexufu, Cardiogrupo and Cardionco.

Keywords

Ilex paraguariensis
Therapeutics
Women's Health
Menopause
Ethnopharmacology
Phytotherapy

Abstract

This systematic review aims to evaluate the potential therapeutic effects of consuming yerba mate (Ilex paraguariensis St. Hil. Aquifoliaceae) for menopausal women. Boolean logical operators and indexers were used: "Ilex paraguariensis" AND "Therapeutics" OR "Disease Prevention" for research on the Virtual Health Library (VHL) platform. The following inclusion criteria were adopted: date of publication (2015 to 2021), language (Portuguese or English), prevention and interventions (Including qualitative and individual participant data reviews). There were 589 results, 195 items were filtered. After, 178 items were disregarded, according to the following exclusion criteria: type of text without free access (10), duplicate text (14) and subjects outside the theme (158). The 13 selected results were grouped according to the follow criteria: a) main applications; b) study type; c) daily dose and route of administration; d) study period; e) main outcomes. Therefore, it can be concluded that it is possible to consume yerba mate (I. paraguariensis) for prevention and complementary treatment of negative outcomes that affect women's health during the menopause period. However, due to reports of toxicity and natural variation, further clinical trials are needed to establish technical criteria in order to ensure the safety and effectiveness of its use in clinical protocols.

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Author(s)

  • Fábio Tonissi Moroni
    Federal University of Uberlândia (UFU), Faculty of Medicine, Department of Internal Medicine. Campus Umuarama, CEP 38408-100, Uberlândia, MG, Brazil.
  • Micaela Lemos Reis
    Federal University of Uberlândia (UFU), Faculty of Medicine, Department of Internal Medicine. Campus Umuarama, CEP 38408-100, Uberlândia, MG, Brazil
  • Raquel Borges-Moroni
    Federal University of Uberlândia (UFU), Institute of Biomedical Sciences, Department of Parasitology. Campus Umuarama, CEP 38405-318, Uberlândia, MG, Brazil
  • José Fausto de Morais
    Federal University of Uberlândia (UFU), Faculty of Mathematics, Campus Santa Monica, CEP 38400-902, Uberlândia, MG, Brazil
  • Nadia Carla Cheik
    Federal University of Uberlândia (UFU), Faculty of Physical Education and Physiotherapy, Physical Education Campus, CEP 38400-678, Uberlândia, MG, Brazil
  • Elmiro Santos Resende
    Federal University of Uberlândia (UFU), Faculty of Medicine, Department of Internal Medicine. Campus Umuarama, CEP 38408-100, Uberlândia, MG, Brazil

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1.
Potential therapeutic effects of yerba mate (Ilex paraguariensis St. Hil. Aquifoliaceae) consumption for menopausal women: a systematic review. Rev Fitos [Internet]. 2022 Sep. 30 [cited 2025 Dec. 24];16(3):380-91. Available from: https://revistafitos.far.fiocruz.br/index.php/revista-fitos/article/view/1257
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