Bioprospection of Caatinga plants with potential for phytomedicine production

Ana Valéria Souza
Camila Hernandes
Danilo Diego de Souza
Evelyn Sophia Silva Costa
Luma dos Passos Bispo
Flávio José Vieira de Oliveira
Ana Maria Soares Pereira

    Ana Valéria Souza

    Brazilian Agricultural Research Corporation (EMBRAPA), CPATSA. BR 428, Km 152, Zona Rural, Caixa Postal 23, CEP 56302-970, Petrolina, PE, Brazil

    holds a degree in Agronomy from the Federal University of Lavras (2001), a Master's in Agronomy (Phytotechnics) from the Federal University of Lavras (2003) and a PhD in Agronomy (Horticulture) from the Universidade Estadual Paulista Júlio de Mesquita Filho (2006). She is currently a researcher at Embrapa Semiárido in the area of Plant Biotechnology Applied to the Environment. She has experience in Agronomy, with an emphasis on Plant Biotechnology, Plant Tissue Culture, Plant Production, Medicinal and Aromatic Plants, Essential Oils, Plant Genetic Resources and Germplasm Conservation.

    Camila Hernandes

    Instituto Israelita de Ensino e Pesquisa Albert Einstein, Avenida Albert Einstein, nº 627, Jardim Leonor, CEP 05652-900, São Paulo, SP, Brazil.

    Graduate, Master and Doctor in Biotechnology. She works as an Associate Researcher at Instituto Israelita de Ensino e Pesquisa Albert Einstein, Hospital Israelita Albert Einstein, in the area of research, development of new biotechnological products, and evaluation of new health technologies. Coordinator of the Entrepreneurship and Innovation in Health Course at the Instituto Israelita de Ensino e Pesquisa Albert Einstein. She has experience in developing R&D projects, and evaluating new health technologies in partnership with industries and Startups. Acts as Manager of Innovation and Partnerships with Startups of the Innovation Board of Hospital Israelita Albert Einstein, Eretz.bio, HIAE Startups incubator.

    Danilo Diego de Souza

    Ouricuri Municipal Environment Agency, Rua Adolfo Soares, nº 125, Centro, CEP 56200-000, Ouricuri, PE, Brazil.

    has a Technical course in Agriculture from IF Sertão-PE (Federal Institute of Sertão Pernambucano) (2009), Bachelor’s Degree in Biological Sciences from UPE (University of Pernambuco) (2012), Master’s in Botany from UFRPE (Federal Rural University of Pernambuco) (2015) and Specialization in Environmental Technology and Sustainability in Semi-Arid Territories by IF Sertão-PE (2018). Professor of Biology at the state education network of Pernambuco and Agricultural Technician at the Municipality of Ouricuri-PE, working at the Municipal Environment Agency (AMMA). Has experience in Botany, with emphasis on Plant Physiology, Plant Biochemistry, Plant Biotechnology, Plant Production, Systematic Botany, Gardening and Landscaping, as well as working in the Environmental Area, with emphasis on Environmental Impact Assessment, Reforestation/Recovery of degraded areas. , Urban Afforestation, Environmental Landscaping, Environmental Management and Environmental Education.

    Evelyn Sophia Silva Costa

    Feira de Santana State University (UEFS), Avenida Transnordestina, Km 0, BR 116, CEP 44036-900, Feira de Santana, Bahia, Brazil

    Biologist from UPE - University of Pernambuco. Master in Plant Genetic Resources from the State University of Feira de Santana (UEFS). Has experience in Biology, with emphasis on Plant Biotechnology, working mainly on the following topics: medicinal plants, in vitro culture of plant cells and tissues, micropropagation, conventional cytogenetics, plant genetic improvement, essential oils, plant extracts and alternative control of bacteria and phytopathogenic fungi. She is currently a doctoral student in biotechnology at the State University of Feira de Santana (UEFS). With emphasis on structural and functional analysis of macromolecules of plant microorganisms with biotechnological potential, working mainly on the following topics: Docking, Virtual Screening, Chemistry, Medicine, Computational and Pharmacology. Professor at the Faculty Inspirar Petrolina-PE.

    Luma dos Passos Bispo

    Rua Pedro Dias de Araújo, nº 26, Cohab Massangano, CEP 56310-530, Petrolina, PE, Brazil

    Graduated in Biological Sciences from the University of Pernambuco-UPE (2012). During the master's degree (2015) in Plant Genetic Resources, he worked mainly in the related areas: aromatic and medicinal plants, extraction and chemical identification of essential oils, plant regulators and vegetative propagation of plant species of the Lippia genus. During her doctorate (2019) in Plant Genetic Resources at the Universidade Estadual de Feira de Santana-UEFS, she worked with the extraction and identification of chemical constituents of essential oils from several plant species, their insecticidal effect and selectivity against useful insects. She is currently a professor at the Pernambuco Department of Education and Sports and at the same time develops work with Aromatherapy.

    Flávio José Vieira de Oliveira

    State University of Bahia (UNEB), Department of Technologies and Social Sciences, Rua Edgar Chastinet, s/n, São Geraldo, CEP 48905-680, Juazeiro, Bahia, Brazil

    He holds a degree in Agronomic Engineering from the Federal Rural University of Pernambuco (1998), a Master's in Agronomy (Soil Sciences) from the Federal Rural University of Pernambuco (2001) and a PhD in Agronomy (Tropical Agriculture) from the Federal University of Paraíba (2009). He is currently a Full Professor at the State University of Bahia-Campus III Juazeiro, where he teaches the subjects of Cartography and Geoprocessing, Agricultural Mechanization and Medicinal, Spice and Aromatic Plants. He has experience in the field of Agronomy, working mainly on the following topics: Vegetable production, Horticulture, Olericulture, Fruticulture, Medicinal plants, Large crops, Precision Agriculture and Agricultural Mechanization.

    Ana Maria Soares Pereira

    University of Ribeirão Preto (UNAERP), Department of Plant Biotechnology, Avenida Costábile Romano, nº 2201, CEP 14096-380, Ribeirão Preto, SP, Brazil.

    He holds a degree in Agronomic Engineering from the Federal Rural University of Pernambuco (1998), a Master's in Agronomy (Soil Sciences) from the Federal Rural University of Pernambuco (2001) and a PhD in Agronomy (Tropical Agriculture) from the Federal University of Paraíba (2009). He is currently a Full Professor at the State University of Bahia-Campus III Juazeiro, where he teaches the subjects of Cartography and Geoprocessing, Agricultural Mechanization and Medicinal, Spice and Aromatic Plants. He has experience in the field of Agronomy, working mainly on the following topics: Vegetable production, Horticulture, Olericulture, Fruticulture, Medicinal plants, Large crops, Precision Agriculture and Agricultural Mechanization.


Keywords

Medicinal plant
Herbal
Lippia grata
Lippia schaueriana
Croton conduplicatus

Abstract

The Caatinga is an exclusively Brazilian biome that has an expressive number of plants with medicinal and aromatic potential in its domain. However, little is known about these native species. The objective of this work was to identify native plants of the Caatinga with medicinal potential and to initiate studies aimed at the domestication of those species identified as promising for the production of phytomedicines. For this, surveys and identifications of medicinal plants used by the population in the Territory of Sertão do São Francisco, in the Pernambuco and Bahia states, were carried out. From this survey, aromatic and essential oil producing species were selected for the analysis of chemical composition, antimicrobial activity tests and pharmacological tests and propagation and cultivation studies. So far, research in these areas has advanced to five species, in different stages - Lippia grata Schauer (Verbenaceae), Lippia schaueriana Mart. ex Schauer (Verbenaceae), Croton conduplicatus Kunth (Euphorbiaceae), Croton sonderianus Müll.Arg. (Euphorbiaceae) and Croton campestris A.St.-Hil. (Euphorbiaceae). However, essential oil extraction and phytochemical analysis were performed for all species collected. Results revealed that the essential oils of these species present contents of major compounds with therapeutic activity and, therefore, these can be interesting for the phytomedicines production.

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Author(s)

  • Ana Valéria Souza
    Brazilian Agricultural Research Corporation (EMBRAPA), CPATSA. BR 428, Km 152, Zona Rural, Caixa Postal 23, CEP 56302-970, Petrolina, PE, Brazil
  • Camila Hernandes
    Instituto Israelita de Ensino e Pesquisa Albert Einstein, Avenida Albert Einstein, nº 627, Jardim Leonor, CEP 05652-900, São Paulo, SP, Brazil.
  • Danilo Diego de Souza
    Ouricuri Municipal Environment Agency, Rua Adolfo Soares, nº 125, Centro, CEP 56200-000, Ouricuri, PE, Brazil.
  • Evelyn Sophia Silva Costa
    Feira de Santana State University (UEFS), Avenida Transnordestina, Km 0, BR 116, CEP 44036-900, Feira de Santana, Bahia, Brazil
  • Luma dos Passos Bispo
    Rua Pedro Dias de Araújo, nº 26, Cohab Massangano, CEP 56310-530, Petrolina, PE, Brazil
  • Flávio José Vieira de Oliveira
    State University of Bahia (UNEB), Department of Technologies and Social Sciences, Rua Edgar Chastinet, s/n, São Geraldo, CEP 48905-680, Juazeiro, Bahia, Brazil
  • Ana Maria Soares Pereira
    University of Ribeirão Preto (UNAERP), Department of Plant Biotechnology, Avenida Costábile Romano, nº 2201, CEP 14096-380, Ribeirão Preto, SP, Brazil.

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How to Cite

1.
Bioprospection of Caatinga plants with potential for phytomedicine production. Rev Fitos [Internet]. 2022 Mar. 4 [cited 2025 Dec. 24];16(Supl. 2):212-26. Available from: https://revistafitos.far.fiocruz.br/index.php/revista-fitos/article/view/1283

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