Chains of medicinal plants and phytotherapeutics and the potential of guarana and andiroba in the state of Amazonas from the perspective of local stakeholders

Dr. Rosana Zau Mafra
OrcID
Dr. Nadja Maria Lepsch da Cunha Nascimento
OrcID
Dr. Maria Beatriz Machado Bonacelli
OrcID
Dr. Ana Lúcia Delgado Assad
OrcID
Dr. Jorge Ivan Rebelo Porto
OrcID
Ms. Gabriela Ramos Andrade
OrcID

    Dr. Rosana Zau Mafra

    Federal University of Amazonas (UFAM), Av. General Rodrigo Octavio Jordão Ramos, 1200, Coroado I, CEP 69067-005, Manaus, AM, Brazil.

    OrcID https://orcid.org/0000-0002-7133-9824

    PhD in Biotechnology from the Federal University of Amazonas (UFAM). Master in Natural Resource Economics from Okayama University (Japan). Specialist in Innovation and Business from FUCAPI and Anderson School of Management (UNM). Graduated in Economics from CIESA. Adjunct Professor in the Department of Economics and Analysis of the Faculty of Social Studies at UFAM. She has experience in the public and private sectors. Between 2021 and 2023, she was the Coordinator of the Postgraduate Program in Intellectual Property and Technology Transfer for Innovation - PROFNIT/UFAM. She participates in the Professional Master's Program in Economics at UFAM. Topics of interest: Amazonian bioindustry; Production Chain of Medicinal Plants and Phytotherapeutics; Intellectual Property; Technology Transfer; Innovation and technology; Entrepreneurship; Scientific startups; Business Economics; Personal finance; Cooperation between companies, ICTs, Government; and Amazonian biodiversity data system.

    Dr. Nadja Maria Lepsch da Cunha Nascimento

    National Institute for Amazon Research (INPA), Rodrigo Otávio Ave, Petropolis, Zip Code 69055-010, Manaus, AM, Brazil.

    OrcID https://orcid.org/0000-0002-0977-4147

    He holds a degree in Biological Sciences from the Universidade Estadual Paulista Júlio de Mesquita Filho/Rio Claro (1987), a specialization in Plant Anatomy and Systematics from the National Museum of Natural History of the Smithsonian Institution (1990), a master's degree in Forest Sciences from the University of São Paulo/ESALq (1996), a PhD in Biology (Ecology) from the National Institute for Amazonian Research (2003) and a sandwich doctorate in Evolution and Population Genetics from Georgetown University (2001). He did a postdoctoral fellowship at the Department of Science and Technology Policy (DPCT) at UNICAMP (2017). She has worked for the Ministry of Science, Technology and Innovation (MCTI) and worked for this Ministry and for the National Institute for Amazonian Research. She is currently a senior science and technology analyst/division chief at the General Coordination of Strategic Health Inputs of the Department of Bioindustry and Strategic Health Inputs/Secretariat of Green Economy, Decarbonization and Bioindustry of the Ministry of Development, Industry, Commerce and Services. She has academic training in the areas of evolution, reproduction and genetics of tropical plant populations and in situ and ex situ conservation of genetic resources. She has experience in Administration, with an emphasis on Planning and Public Policies for Science and Technology, working mainly on the following topics: organization and institutional change, the Amazon, phytotherapeutics, medicinal plants, access to genetic heritage and associated traditional knowledge, and biodiversity. She was deputy coordinator of the Coordination of Policies and Programs in Biodiversity and worked in the Fundraising Advisory Office at the Ministry of Science, Technology and Innovation (MCTI), representing this Ministry in the Interministerial Working Group for Analysis of Environmental Projects GTAP (Secretariat of International Economic Affairs - SAIN/MPOG), working at the Global Environment Facility - GEF, IDB and BIRD. She was general manager of the Biodiversity Research Program PPBio and coordinator of the Cooperation and Exchange Coordination at INPA. She was a counselor at the Genetic Heritage Management Council - CGEN for MCTI and INPA and at CONAMA and CONABIO for MCTI. She was a representative of INPA on the Management Council of the BioAmazonas Pole of the Biodiversity Routes of the Ministry of Regional Development and works on several initiatives focusing on the production chain of phytotherapeutics of Amazonian medicinal plants.

    Dr. Maria Beatriz Machado Bonacelli

    State University of Campinas (UNICAMP), Zeferino Vaz University City, Barão Geraldo, ZIP Code 13083-970, Campinas, SP, Brazil.

    OrcID https://orcid.org/0000-0003-0795-7684

    Full Professor (MS5.3, Associate Professor III) at the Department of Science and Technology Policy (DPCT/IG/Unicamp). Graduated in Economics (IE/State University of Campinas, 1985), with a specialization in Economics of the Agri-Food System (CeFAS, Viterbo, Italy, 1988), master's degree in Science and Technology Policy (DPCT/IG/Unicamp, 1992) and PhD in Economics (Université des Sciences Sociales de Toulouse, France, 1996). Advisor III to the Pro-Rectory of Graduate Studies at Unicamp (Jan. 2019-Mar. 2021). General Coordinator of Graduate Studies at the Institute of Geosciences (IG) (2013-2015). Coordinator of the PPG-PCT (2016-2018; 2011-2013). Head of Department (DPCT, 2009-2011). Associate Researcher at the Study Group on Research and Innovation Organization (GEOPI/DPCT), INCT-PPED (UERJ/UFRJ/Unicamp) and the Study Group on University-Society Relations (GRUS/Unicamp). Participates in the Network - Legal Center of the Innovation and Competitiveness Observatory (IEA and Law School/USP). President (April 2018-) and Member (since 2011) of the Evaluation Committee of the Management Contract between CNPEM and MCTIC. Participated in the preparation of the STI Master Plan of the State of São Paulo 2014-2015. Winner, in 2016, of the 58th. Jabuti Award, 2nd place in the Economics and Administration category as co-editor of the work "Intellectual Property and Innovation in Agriculture". Main lines and themes of research: Economics of Technology and Innovation; Planning and Management of STI; Innovation Systems and Ecosystems; University-Society Relationship.

    Dr. Ana Lúcia Delgado Assad

    Brazilian Association for the Study of Bees – ABELHA, Rua João Cachoeira, 488, Conj. 302, Vila Nova Conceição, CEP 04535-001, São Paulo, SP, Brazil.

    OrcID https://orcid.org/0009-0008-8445-905X

    She holds a degree in Economics from the Catholic University of Brasília (1980) and a PhD in Science and Technology Policy from the State University of Campinas (2000). She coordinated the Biotechnology and Health area of ​​the Ministry of Science and Technology from 1991 to 1996 and from 2000 to July 2004. She was General Coordinator of Cooperation at the Directorate of Institutional Cooperation of CNPq from 2009 to February 2012, and Head of the Advisory Board for Sectoral Funds and Deputy Executive Secretariat of the Ministry of Science, Technology and Innovation from August 2012 to April 2014. She is a visiting professor at the Biodiversity and Biotechnology Network of the Northern Region Bionorte and at the Multi-institutional Postgraduate Program in Biotechnology PPGBiotec/UFAM.

    Dr. Jorge Ivan Rebelo Porto

    National Institute for Amazon Research (INPA), Rodrigo Otávio Ave, Petropolis, Zip Code 69055-010, Manaus, AM, Brazil.

    OrcID https://orcid.org/0000-0003-1393-6492

    Dr. Jorge Ivan Rebelo Porto, INPA - Senior Researcher A-III. Graduated in Biological Sciences - Medical Modality (Biomedical). Completed his master's and doctorate in Freshwater Biology and Inland Fisheries from INPA. Published 45 articles in specialized journals and more than a hundred abstracts in conference proceedings. Has published 4 book chapters. Participated in the development of technological products, including the application for two biotechnology patents. Supervises/co-supervises master's dissertations, doctoral theses, scientific initiation works and course completion works. Participates in several research projects, being in some cases coordinator. Works in the area of ​​Genetics, with emphasis on Genomics, Cytogenetics and Molecular Biology. Collaborates as a reviewer of scientific articles and served on the editorial board of the journal Acta Amazonica. In his professional activities, he interacted with more than a hundred collaborators. In the area of ​​management, he was Head of the Department of Aquatic Biology, Head of General Postgraduate Studies at INPA and PPG-Genetics, Technical-Scientific Director at FAPEAM, Head of the INPA Research Center in Santarém-PA, responsible for the Scientific Management of the Large-Scale Biosphere/Atmosphere Program in the Amazon LBA in Santarém-PA, Research Coordinator at the National Institute for Amazonian Research (INPA), President, Secretary and Treasurer of the Brazilian Society of Genetics-North Region. He was a scholarship holder at the State Secretariat of Science and Technology-AM. He served on the Board of Directors of the Biodiversity and Biotechnology Network of the Northern Region BIONORTE. He works in the advisory and evaluation of projects and programs of FAPEAM (Amazonas), FAPESPA (Pará), CNPq and Capes.

    Ms. Gabriela Ramos Andrade

    National Institute for Amazon Research (INPA), Rodrigo Otávio Ave, Petropolis, Zip Code 69055-010, Manaus, AM, Brazil.

    OrcID https://orcid.org/0000-0002-5942-0945

    Environmental Manager from the Luiz de Queiroz College of Agriculture (ESALQ)/University of São Paulo (USP). Specialist in Amazon Business Management from the Rainforest Social Business School of the College of Social Sciences (ESO)/Amazonas State University (UEA). She was a FAPEAM scholarship holder from the National Institute of Amazonian Research (INPA) in the project "Prospecting and technical-productive prioritization for the integration of the Amazonian phytotherapeutic chain" and manager of the AVSI BRASIL project in Roraima "Boa Vista Acolhedora: an intersectoral model of circular economy and agroecology", funded by the European Union and Banco do Brasil Foundation. She has experience in Ecology, with emphasis on Permaculture, Agroecology and Environmental Education. She works with: project management, regenerative agriculture, sustainable agroecosystems, circular economy, ethnobotany and socio-environmental technologies.


Keywords

Production chain
Traditional knowledge
Institutional environment
Paullinia cupana
Carapa guianensis

Abstract

Although the Amazon region has a rich biodiversity, the number of herbal medicines derived from native
medicinal plants is small, as indicated by databases and the literature, this paper aims to present the results
of a survey carried out with researchers, managers, businessman and technicians from different Amazonian
organizations, taking into account actions, policies and market conditions that encourage or limit the use of
medicinal plants and the development of herbal medicine production in the region, focusing on two species,
guaraná and andiroba, given traditional knowledge, academic studies and local production of these species.
Field research took place through interviews outlined into three themes - production chain, characteristics
of the two species and institutional environment. The study concluded that guaraná and andiroba still arise
little interest for the interviewees, there is no consensus on which phase(s) of the chain the gaps are greatest,
there is a need to reinforce the training and developing of human resources in agricultural practices and
plant management, and there is a lack of effective policies and strategies to leverage partnerships among
universities, scientific institutions and firms. 

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Author(s)

  • Dr. Rosana Zau Mafra
    Federal University of Amazonas (UFAM), Av. General Rodrigo Octavio Jordão Ramos, 1200, Coroado I, CEP 69067-005, Manaus, AM, Brazil.
    https://orcid.org/0000-0002-7133-9824
  • Dr. Nadja Maria Lepsch da Cunha Nascimento
    National Institute for Amazon Research (INPA), Rodrigo Otávio Ave, Petropolis, Zip Code 69055-010, Manaus, AM, Brazil.
    https://orcid.org/0000-0002-0977-4147
  • Dr. Maria Beatriz Machado Bonacelli
    State University of Campinas (UNICAMP), Zeferino Vaz University City, Barão Geraldo, ZIP Code 13083-970, Campinas, SP, Brazil.
    https://orcid.org/0000-0003-0795-7684
  • Dr. Ana Lúcia Delgado Assad
    Brazilian Association for the Study of Bees – ABELHA, Rua João Cachoeira, 488, Conj. 302, Vila Nova Conceição, CEP 04535-001, São Paulo, SP, Brazil.
    https://orcid.org/0009-0008-8445-905X
  • Dr. Jorge Ivan Rebelo Porto
    National Institute for Amazon Research (INPA), Rodrigo Otávio Ave, Petropolis, Zip Code 69055-010, Manaus, AM, Brazil.
    https://orcid.org/0000-0003-1393-6492
  • Ms. Gabriela Ramos Andrade
    National Institute for Amazon Research (INPA), Rodrigo Otávio Ave, Petropolis, Zip Code 69055-010, Manaus, AM, Brazil.
    https://orcid.org/0000-0002-5942-0945

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Chains of medicinal plants and phytotherapeutics and the potential of guarana and andiroba in the state of Amazonas from the perspective of local stakeholders. Rev Fitos [Internet]. 2025 Apr. 28 [cited 2025 Dec. 8];19:e1616. Available from: https://revistafitos.far.fiocruz.br/index.php/revista-fitos/article/view/1616
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