Ethnobotanical/ethnopharmacological analysis of bottles based on medicinal plants from a market in Fortaleza-CE

Me. Fabio Morais da Silva
OrcID
Mr. Francisco Iuri da Silva Martins
OrcID
Mr. José Aurélio de Almeida Martins
OrcID
Dr. Bruno Bezerra da Silva
OrcID
Dr. João Xavier da Silva Neto
OrcID
Dr. Luanne Eugênia Nunes
OrcID
Dr. Maria do Socorro Moura Rufino
OrcID
Dr. Jeferson Falcão do Amaral
OrcID

    Me. Fabio Morais da Silva

    University of International Integration of Afro-Brazilian Lusophony (UNILAB), Avenida da Abolição, 3, Centro, CEP 62790-000, Redenção, CE, Brazil.

    OrcID https://orcid.org/0000-0002-5317-6427

    Master in Sociobiodiversity and Sustainable Technology - Unilab-CE (2023) Graduated in Pharmacy from Uninassau (2023). Postgraduate in Biotechnology and Molecular Biology UECE (2022). Postgraduate in Clinical Pharmacology from Uniateneu (2019). Graduated in Biology from Universidade Estadual Vale do Acaraú (2017). Has experience in Teaching in Basic Education (Science and Biology), working as a teacher of Elementary and High School. I was a member of the Research Group - POLIFIBAN (Polyphenols, antioxidants and Vitamin C in health) and a Funcap scholarship holder. I work in the following lines of research: Rational use of Medicinal Plants and Phytotherapeutics. Pharmaceutical Care. Biotechnology. Pharmacology. General Biology.

    Mr. Francisco Iuri da Silva Martins

    University of International Integration of Afro-Brazilian Lusophony (UNILAB), Avenida da Abolição, 3, Centro, CEP 62790-000, Redenção, CE, Brazil.

    OrcID https://orcid.org/0000-0003-3524-5609

    Undergraduate in Pharmacy from the University of International Integration of Afro-Brazilian Lusophony (UNILAB). He was a scholarship holder, volunteer and research and extension collaborator. He is currently a PIBIC/UNILAB scholarship holder, whose project aims to compare the quality of life and sleep between Brazilian and international students.

    Mr. José Aurélio de Almeida Martins

    University of International Integration of Afro-Brazilian Lusophony (UNILAB), Avenida da Abolição, 3, Centro, CEP 62790-000, Redenção, CE, Brazil.

    OrcID https://orcid.org/0000-0002-6086-7808

    Undergraduate in Pharmacy from the University of International Integration of Afro-Brazilian Lusophony (UNILAB). Scholarship holder of the Institutional Program of Scientific Initiation Scholarships - PIBIC of the project called "Study of the influence of sex in mice subjected to the model of autism induced by maternal separation". Member of the Research and Extension Group on Medication Use (GPUMED). Member of the Research and Studies Group on Public Health (GPESP). President of the Academic League of Clinical Pharmacy (LIAFAC). Interested in the area of ​​Mental Health and Neuropsychopharmacology. Currently, he works as a volunteer monitor in the discipline of General Pharmacology.

    Dr. Bruno Bezerra da Silva

    State University of Ceara, Dr. Silas Munguba Avenue, 1700, Itaperi, Zip Code 60714-903, Fortaleza, CE, Brazil.

    OrcID https://orcid.org/0000-0002-9881-201X

    PhD in Biotechnology (area of ​​concentration: Health) from the Northeast Biotechnology Network (RENORBIO), Specialist in Higher Education Teaching from SENAC University Center (2019) and Bachelor in Nutrition from the State University of Ceará (2014). Member of the Biotechnology Innovation in Health Research Group at the State University of Ceará (UECE). He worked as a researcher at GreenBean Biotecnologia, developing cloning and production of heterologous proteins through a transient expression system in plants. Professor of Molecular Biology in the Specialization courses in Biotechnology and Molecular Biology Applied to Health and in the Specialization course in Clinical Analysis and Quality Management in Laboratories. He has experience in the production of recombinant proteins for biotechnological application in neglected tropical diseases. He also has experience in analyzing gene expression in experimental models of chronic non-communicable diseases. Topics of interest: applied biochemistry and molecular biology; immune system x nutrition interface.

    Dr. João Xavier da Silva Neto

    State University of Ceara, Dr. Silas Munguba Avenue, 1700, Itaperi, Zip Code 60714-903, Fortaleza, CE, Brazil.

    OrcID https://orcid.org/0000-0002-6981-2838

    PhD and Master in Biochemistry (Federal University of Ceará), Biologist (State University of Rio Grande do Norte). Experienced in general biology, general physiology, diabetes and obesity pathology, general microbiology (with emphasis on microorganisms that are pathological to humans) and bioremediation of soils and polluted waters. He also has extensive experience in prospecting and characterizing natural biomolecules with biological activity of clinical interest. Researcher at the Laboratory of Biotechnology and Molecular Biology and the research group entitled Biotechnological Innovation in Health. Currently working on the production of diagnostic tests for viruses of clinical importance (flavivirus and SARS-CoV-2) and production of immunizers against viruses of clinical importance (flavivirus and SARS-CoV-2).

    Dr. Luanne Eugênia Nunes

    University of International Integration of Afro-Brazilian Lusophony (UNILAB), Avenida da Abolição, 3, Centro, CEP 62790-000, Redenção, CE, Brazil.

    OrcID https://orcid.org/0000-0001-6524-0994

    She holds a degree in Pharmacy from the State University of Paraíba (2011) and a Master's degree in Pharmaceutical Sciences from the State University of Paraíba (2014). She holds a PhD in Pharmaceutical Sciences from the Federal University of Pernambuco (2019). She has experience in determining the biological activity of natural products, with an emphasis on obtaining bioactive molecules with antimicrobial action. She is currently an adjunct professor at the Institute of Health Sciences (ICS) of the University of International Integration of Afro-Brazilian Lusophony - UNILAB.

    Dr. Maria do Socorro Moura Rufino

    University of International Integration of Afro-Brazilian Lusophony (UNILAB), Avenida da Abolição, 3, Centro, CEP 62790-000, Redenção, CE, Brazil.

    OrcID https://orcid.org/0000-0003-3450-9481

    Since her undergraduate degree in Agricultural Engineering, she has dedicated herself to the study of bioactive compounds present in tropical fruits and related topics. Her master's degree focused on the study of nutritional compounds present in cashew. In 2008, she completed her doctorate, including a PhD internship abroad in Nutritional Biochemistry at the Department of Metabolism and Nutrition (ICTAN/CSIC), Madrid (ES). In 2010, she was recognized with the Capes Thesis Award/2009, for her original research on bioactive compounds, dietary fiber and antioxidant activity in tropical fruits. In 2010, she completed a Post-Doctorate (PNPD/CAPES) in Food Science and Technology at UFC. She is currently an Associate Professor (started in 2012) at the University for the International Integration of Afro-Brazilian Lusophony (UNILAB), a federal public institution whose mission is international cooperation with CPLP countries. She is a Permanent Professor in the MASTS/Unilab Graduate Program. From 2012 to 2014, she participated in the management of the University, assuming management positions, among them the Coordination of Research and Graduate Studies, Pro-Rectory of Research, Graduate Studies and Extension and Pro-Rectory of Institutional Relations. She is leader of the POLIFIBAN/CNPq research group (Polyphenols, antioxidants and dietary fiber in health). Among her recent works, the following stand out: participation as author of a book chapter by the Royal Society of Chemistry, Cambridge (UK); participation as author of a book chapter by Elsevier (RJ); Luis Noé Fernández Award, Antioxidants-Fiber group, Alimerka Foundation, Spain; lectures and courses taught in Brazil and abroad. She has experience in the area of ​​Food Science and Technology, working mainly on the following topics: Food Biochemistry, Dietary Bioactive Compounds (polyphenols and fibers), Public Health and Food and Nutritional Security. Manager of the Biochemistry Laboratory (IDR-Unilab). Member of the Chamber of Agronomic and Veterinary Sciences (CAV/FUNCAP). Ad hoc consultant for FUNCAP and FAPESB. Member of the National Higher Education Assessment System (BASis/INEP).

    Dr. Jeferson Falcão do Amaral

    University of International Integration of Afro-Brazilian Lusophony (UNILAB), Avenida da Abolição, 3, Centro, CEP 62790-000, Redenção, CE, Brazil.

    OrcID https://orcid.org/0000-0003-0426-0347

    Adjunct Professor Class C4 at the University of International Integration of Afro-Brazilian Lusophony (UNILAB). Graduated in Pharmacy from the Federal University of Ceará (2000), Master in Pharmacology from the Federal University of Ceará (2004) and PhD in Pharmacology from the same University (2010). Specialist in Strategic Management of Higher Education Institutions-IES (FAMETRO). Specialist in Pharmaceutical Care and Clinical Pharmacy (IPOG). Integrative Therapist - Auricular Acupuncture, Auriculotherapy, Clinical Cupping Therapy, Clinical Massage Therapy, Shiatsu, Foot Reflexology and Seitai/New Seitai Chiropractic (Harmony Therapies). Training and Specialization in Acupuncture in progress (ABA). Specialization in Phytotherapy and Prescription of Phytotherapeutics in progress (Faculdade Metropolitana). Specialization in Mental Health in progress (FAVENI). Ongoing Clinical Psychoanalysis Training Course (Brazilian Institute of Clinical Psychoanalysis - IBPC). Professor of the Pharmacy Course ICS/UNILAB (Pharmaceutical Semiology, Clinical Pharmacy, Internship in Pharmaceutical Assistance, Internship in Clinical Pharmacy, Deontology and Introduction to the Pharmacy Course). Permanent Professor of the Professional Postgraduate Program in Family Health (PPGSF/RENASF/FIOCRUZ). Permanent Professor of the Academic Master's Degree in Sociobiodiversity and Sustainable Technologies (MASTS/UNILAB). Professor Advisor for TCCs of the Uni/Multiprofessional Residency of ESP-CE (TOPIC: Mental/Collective Health). Coordinator of the Research and Extension Group on Medication Use (GPUMed - UNILAB). Professor/Advisor of the Academic League of Clinical Pharmacy (LIAFAC/Pharmacy Course/ICS). Coordinator of the Distance Learning Center of Redenção-CE (IEAD/UNILAB). Clinical Pharmacist at the Center for Comprehensive Health Care (CAIS/ICS/UNILAB). Member of the Technical Advisory Committee for Pharmaceutical Education (CRF-CE). Member of the Technical Advisory Committee for Integrative and Complementary Practices in Health - PICS (CRF-CE). Effective member of the Chamber of Medical and Health Sciences of FUNCAP. Has experience in the area of ​​Academic Management and Distance Learning Management. Has experience in the Health area (Clinical Pharmacy, Pharmaceutical Assistance, Integrative Therapies, Pharmaceutical Office, Pharmaceutical Prescription and Teaching). Works as a Researcher and Extensionist in the following lines of study: Clinical Pharmacy; Pharmaceutical Care; Mental Health and Neuropsychopharmacology; Rational Use of Medicines/Medicinal Plants/Phytotherapeutics, Integrative Therapies, Education/Health Promotion and Pharmaceutical Assistance.


Keywords

Medicinal plants
Herbaric medicine
Natural products
Phytotherapy

Abstract

The objective of this work was to analyze, according to the literature, whether the medicinal plants that are described on the bottle labels treat the reported pathology, through the spontaneous declaration of the vendors. A collection of 10 bottles of medicinal plants was carried out, which were chosen at random, with different therapeutic purposes and with legible labels. These were acquired with their own financial resources to carry out this study. The bottles were also analyzed for the construction of tables with the identification of the scientific name, popular name, the parts of use of each species of plant, verifying if the purpose of each one of them corresponds with the pathology described on the labels of the bottles that were analyzed. . Furthermore, a search was carried out in the databases and the information collected was compared with the current literature. Research shows that the use of bottles can cause adverse reactions and/or intoxications, which could become a relevant public health problem. It is inferred that in order to avoid adverse reactions, it is necessary to carry out health education and awareness-raising work with herbalists and the population, by professionals specializing in medicinal plants, such as pharmacists.

References

  1. Moraes EF, Mezzomo TR, Oliveira VB. Conhecimento e uso de plantas medicinais por usuários de unidades básicas de saúde na região de Colombo, PR. Rev Bras Ciênc Saúde. 2018; 22 (1): 57-64. [https://doi.org/10.22478/ufpb.2317-6032.2018v22n1.30038].
  2. Griz SAS, Matos-Rocha TJ, Santos AF, Costa JG, Mousinho KC. Medicinal plants profile used by the 3rd District population of Maceió-AL. Braz J Biol. 2017; 77(4): 794-802. [https://doi.org/10.1590/1519-6984.01116].
  3. Passos MMB, Albino RC, Feitoza-Silva M, Oliveira DR. A disseminação cultural das garrafadas no Brasil: um paralelo entre medicina popular e legislação sanitária. Saúde Debate. 2018; 42 (116): 248-262. [https://doi.org/10.1590/0103-1104201811620].
  4. Mattos G, Camargo A, Souza CA, Zeni ALB. Plantas medicinais e fototerápicas na atenção primária em saúde: percepção dos profissionais. Ciênc Saúde Colet. 2018; 23 (11). [https://doi.org/10.1590/1413-812320182311.23572016].
  5. Pires IFB, Sousa AA, Lima CA, Costa JD, Feitosa MHA, Costa SM. Plantas medicinais: cultivo e transmissão de conhecimento em comunidade cadastrada na Estratégia Saúde da Família. Rev Bras Pesq Saúde. 2016; 18(4): 37-45. [https://periodicos.ufes.br/rbps/article/view/16729/11559].
  6. Alves CAB, Silva S, Belarmino NALA, Souza RS, Silva DR, Alves PRR, et al. Comercialização de plantas medicinais: um estudo etnobotânico na feira livre do Município de Guarabira, Paraíba, nordeste do Brasil. Gaia Scientia. 2016; 10 (4): 390–507. [http://dx.doi.org/10.21707/gs.v10.n04a31].
  7. Lopes GFG, Pantoja SCS. Levantamento das espécies de plantas medicinais utilizadas pela população de Santa Cruz – Rio de Janeiro-RJ. Rev Eletr Novo Enfoq. 2013; 16 (16): 62-80. [http://revistaea.org/artigo.php?idartigo=1709].
  8. Bueno MJA. Manual de plantas medicinais e fitoterápicos utilizados na cicatrização de feridas. Pouso Alegre; 2016. xiv, 118f. Dissertação de Mestrado [em Ciências Aplicadas à Saúde] - Universidade do Vale do Sapucaí, UNIVAS, Pouso Alegre, MG, 2016.
  9. Gil AC. Como elaborar projetos de pesquisa. 6th ed. São Paulo: Atlas; 2017.
  10. Badke MR, Barbieri RL, Ribeiro MV, Ceolin T, Martínez-Hernáez A, Alvim NAT. Significados da utilização de plantas medicinais nas práticas de auto atenção à saúde. Rev Esc Enferm USP. 2019; 53: 1-8. [https://doi.org/10.1590/S1980-220X2018047903526]
  11. Gan JJ, Liu C, Li H, Wang S, Wang Z, Kang Z, et al. Accelerated wound healing in diabetes by reprogramming the macrophages with particle-induced clustering of the mannose receptors. Biomaterials. 2019; 216: 119-340. [https://pubmed.ncbi.nlm.nih.gov/31357007/]
  12. Medeiros ALA, Câmara YB, Cardoso MGA, Melo TCS, Freire AS. Influência de extratos de folhas e frutos de Azadirachta indica A. Juss em sementes de Leucaena leucocephala (Lam.) R. de Wit; 2017. Anais II Congresso Internacional da Diversidade do Semiárido: Realize Eventos Científicos e Editora.
  13. Falcão TR, Rodrigues CAO, Araújo AA, Medeiros CACX, Soares LAL, Ferreira MRA, et al. Crude extract from Libidibia ferrea (Mart. ex. Tul.) L.P. Queiroz leaves decreased intra articular inflammation induced by zymosan in rats. BMC Complement Altern Med. 2019; 19(1): 47. [https://pubmed.ncbi.nlm.nih.gov/30755211/]
  14. Santana GS, Oliveira Filho JG, Egea MB. Características tecnológicas de farinhas vegetais comerciais. Rev Agric Neotrop. 2017; 4(2): 88-95. [https://doi.org/10.32404/rean.v4i2.1549]
  15. Araújo JMD, Silva AP, Cândido MB, Silva TWM, Andrade Júnior FP. Ethnopharmacological study of Anacardium occidentale: a brief review. Res Soc Dev. 2020; 9(8). [https://doi.org/10.33448/rsd-v9i8.5802]
  16. Moura MHC, Cunha MG, Alezandro MR, Genovese MI. Phenolic-rich jaboticaba (Plinia jaboticaba (Vell.) Berg) extracts prevent high-fat-sucrose diet-induced obesity in C57BL/6 mice. Food Res Int. 2018; 107: 48-60. [https://pubmed.ncbi.nlm.nih.gov/29580510/]
  17. Lee WY, Lee CY, Kim YS, Kim CE. The Methodological Trends of Traditional Herbal Medicine Employing Network Pharmacology. Biomolecules. 2019; 9(8): 362. [https://pubmed.ncbi.nlm.nih.gov/31412658/]
  18. Organização Pan-Americana da Saúde. (OPAS). Folha informativa: Câncer 2018. [acesso em: 10 jul. 2022]. Disponível em: [https://www.paho.org/pt/topicos/cancer].
  19. Prado MASA, Matsuok JT, Giotto AC. Importância das Farmácias Vivas no âmbito da produção dos medicamentos fitoterápicos. REIS. 2018; 1(1): 32–37.
  20. Cardoso IC, Pereira HMG, Tappin MRR, Behrens MD. Influência da técnica de extração e do tamanho de partícula do material vegetal no teor de compostos fenólicos totais da tintura das folhas de Alpinia zerumbet. Rev Fitos. 2017; 11: 62-68. [https://www.arca.fiocruz.br/handle/icict/21132]
  21. Gonçalves FS. Mecanismos de ação relacionados a atividade antiúlcera de Kalanchoe pinnata. São Paulo; 2017. Tese de Doutorado [Programa de Pós-Graduação em Fármacos e Medicamentos] - Universidade de São Paulo, USP, São Paulo; SP. 2017.
  22. Fadin DA. Aspectos da biologia e do controle químico de Spermacoce verticillata L. Araras. 2017. Dissertação de Mestrado [Programa de Pós-Graduação em Agronomia/Ambiente] - Universidade Federal de São Carlos, UFSCAR, Araras, SP, 2017. [https://repositorio.ufscar.br/handle/ufscar/9485?show=full].
  23. Moreski DAB, Leite-Mello EVS, Bueno FG. Ação cicatrizante de plantas medicinais: um estudo de revisão. Arq Cienc Saúde UNIPAR. 2018; 22(1): 63-69. [https://pesquisa.bvsalud.org/portal/resource/pt/biblio-883545]
  24. Medeiros AS, Santos EMC, Lima RWS, Nascimento VX, Souza MA. Constância dos grupos da macrofauna edáfica em cultivo de quiabo, Alagoas. BJAER. 2019; 2(6): 1891-1895. [https://ojs.brazilianjournals.com.br/ojs/index.php/BJAER/article/view/5386]
  25. Bandeira MGL, Rebouças GG, Oliveira-Filho RD, Abrantes MR, Silva MDC, Silva JBA. Perfil de sensibilidade de Staphylococcus spp. isolados de alimentos de origem animal ao extrato bruto e a fração proteica obtida de Lippia alba (Mill.) N.E. Brown. Rev Bras Med Vet. 2016; 38(2): 163-167. [https://bjvm.org.br/BJVM/article/view/227/150].
  26. Barbosa GCL, Ferraz JL, Alves LA. Impactos de medicamentos benzodiazepínicos na qualidade de vida de pessoas portadoras de transtorno de ansiedade generalizada. Res Soc Dev. 2021; 10(15). [http://dx.doi.org/10.33448/rsd-v10i15.23202].
  27. Holz DT, Vogel-Ely C, Muller NTG, Fasolo D. Conhecimento empírico versus conhecimento científico e análise fotoquímica de espécies medicinais cultivadas por uma associação de Santo Ângelo, Rio Grande do Sul. Rev Biocienc. 2013; 19(1): 12-23. [https://periodicos.unitau.br/ojs/index.php/biociencias/article/view/1661/1183].
  28. Moghim H, Taghipoor S, Shahinfard N, Kheiri S, Heydari Z, Rafieian S. Antifungal effects of Alliumas calonicum, Marticaria chamomilla and Stachys lavandulifolia extracts on Candida albicans. J HerbMed Pharmacol. 2014; 3(1): 9-14. [https://herbmedpharmacol.com/Article/JHP_20150527121021].
  29. Carneiro ALC, Comarrela L. Principais interações entre plantas medicinais e medicamentos. Rev Saúde Desenv. 2016; 9(5). [https://www.revistasuninter.com/revistasaude/index.php/saudeDesenvolvimento/article/view/491].

Author(s)

  • Me. Fabio Morais da Silva
    University of International Integration of Afro-Brazilian Lusophony (UNILAB), Avenida da Abolição, 3, Centro, CEP 62790-000, Redenção, CE, Brazil.
    https://orcid.org/0000-0002-5317-6427
  • Mr. Francisco Iuri da Silva Martins
    University of International Integration of Afro-Brazilian Lusophony (UNILAB), Avenida da Abolição, 3, Centro, CEP 62790-000, Redenção, CE, Brazil.
    https://orcid.org/0000-0003-3524-5609
  • Mr. José Aurélio de Almeida Martins
    University of International Integration of Afro-Brazilian Lusophony (UNILAB), Avenida da Abolição, 3, Centro, CEP 62790-000, Redenção, CE, Brazil.
    https://orcid.org/0000-0002-6086-7808
  • Dr. Bruno Bezerra da Silva
    State University of Ceara, Dr. Silas Munguba Avenue, 1700, Itaperi, Zip Code 60714-903, Fortaleza, CE, Brazil.
    https://orcid.org/0000-0002-9881-201X
  • Dr. João Xavier da Silva Neto
    State University of Ceara, Dr. Silas Munguba Avenue, 1700, Itaperi, Zip Code 60714-903, Fortaleza, CE, Brazil.
    https://orcid.org/0000-0002-6981-2838
  • Dr. Luanne Eugênia Nunes
    University of International Integration of Afro-Brazilian Lusophony (UNILAB), Avenida da Abolição, 3, Centro, CEP 62790-000, Redenção, CE, Brazil.
    https://orcid.org/0000-0001-6524-0994
  • Dr. Maria do Socorro Moura Rufino
    University of International Integration of Afro-Brazilian Lusophony (UNILAB), Avenida da Abolição, 3, Centro, CEP 62790-000, Redenção, CE, Brazil.
    https://orcid.org/0000-0003-3450-9481
  • Dr. Jeferson Falcão do Amaral
    University of International Integration of Afro-Brazilian Lusophony (UNILAB), Avenida da Abolição, 3, Centro, CEP 62790-000, Redenção, CE, Brazil.
    https://orcid.org/0000-0003-0426-0347

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How to Cite

1.
Ethnobotanical/ethnopharmacological analysis of bottles based on medicinal plants from a market in Fortaleza-CE. Rev Fitos [Internet]. 2024 Dec. 18 [cited 2025 Feb. 3];18:e1655. Available from: https://revistafitos.far.fiocruz.br/index.php/revista-fitos/article/view/1655
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