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Characterization of the physicochemical profile, of Chamomile (Matricaria recutita L., Asteraceae) plant extracts

    Dr. Natasha Alves Rocha

    State University of Piauí (UESPI), Department of Postgraduate Studies in Chemistry, Torquato Neto Campus, 2231, Pirajá, CEP 64002-150 - PI, Brazil.

    OrcID https://orcid.org/0000-0003-1337-2885

    Graduated in Chemistry from the State University of Piauí (2016-2021). Researcher in the Scientific Initiation Scholarship Program (2019-2020). FNDE scholarship holder in the Tutorial Education Program in Chemistry (2017-2021). Master's degree in Chemistry from the Graduate Program in Chemistry at the State University of Piauí (2021-2023). PhD in Chemistry from the Graduate Program in Chemistry at the Federal University of São Carlos (2023-2027). Specialist in Chemistry of Natural Products with emphasis in the areas of Phytochemical Bioprospecting and Micromolecular Biochemistry of Microorganisms. He is currently a CAPES scholarship holder with ongoing research at the Laboratory of Micromolecular Biochemistry of Microorganisms in the Chemistry Department of the Federal University of São Carlos, developing research related to the elucidation by Mass Spectrometry and Nuclear Magnetic Resonance (1H and 13C) of antibiotic molecules produced by mangrove microorganisms.

    Teacher Letícia Geovanna Cartonilho Siqueira

    State University of Piauí (UESPI), Department of Postgraduate Studies in Chemistry, Torquato Neto Campus, 2231, Pirajá, CEP 64002-150 - PI, Brazil.

    OrcID https://orcid.org/0000-0003-0603-4722

    Graduated in Chemistry from the State University of Piauí.

    Mr. William da Silva Sousa

    State University of Piauí (UESPI), Department of Postgraduate Studies in Chemistry, Torquato Neto Campus, 2231, Pirajá, CEP 64002-150 - PI, Brazil.

    OrcID https://orcid.org/0000-0002-7652-3460

    He is currently studying for a degree in chemistry at the State University of Piauí - UESPI.

    Dr. Girlene Soares de Figueirêdo

    Federal University of Piauí (UFPI), Department of Parasitology and Microbiology, Campus Ministro Petrônio Portella, Ininga, CEP 64049-550, PI, Brazil.

    OrcID https://orcid.org/0000-0002-6710-1549

    She holds a degree in Biology from the Federal University of Piauí (2001) and a master's degree in Fungal Biology from the Federal University of Pernambuco (2005). She holds a PhD (2010) in Biotechnology from the Federal University of Amazonas. She is currently an Adjunct Professor I at the Federal University of Piauí, in the Department of Parasitology and Microbiology. She has experience in the area of ​​Microbiology, with an emphasis on Mycology.

    Dr. Johnnatan Duarte de Freitas

    Federal Institute of Alagoas (IFAL), Department of Chemistry, Campus Centro, Centro, CEP 57020-600, AL, Brazil.

    OrcID https://orcid.org/0000-0002-6977-3322

    Full Professor of the Chemistry Coordination of the Federal Institute of Alagoas (IFAL/Maceió). PhD and Master in Chemistry and Biotechnology from the Federal University of Alagoas (UFAL). Graduated in Chemistry (2001) and Geography (2023) from UFAL. He is currently a Productivity Scholar in Technological Development and Innovative Extension - DT (CNPq Call 08/2022) and leader of the Research Group in Synthesis, Chemical Analysis and Characterization of Materials (GSAQCM/IFAL - Maceió Campus), where he develops Basic and Applied Research, Innovation and Technological Development work, advising Scientific Initiation and Professional Master's students. At the stricto sensu postgraduate level, he is a permanent member of the Postgraduate Program in Environmental Technologies (Master's Degree PPGTEC/IFAL - Marechal Deodoro Campus) and a collaborator of the Doctoral Program in Materials at UFAL (PPG Materiais/UFAL - Maceió Campus). He has experience in the area of ​​Chemistry, with emphasis on Organic Synthesis and Natural Products. He also works in Instrumental Analysis and Material Characterization, since he is a professor of the subjects offered in IFAL courses and was trained and certified by Shimadzu do Brasil to operate and perform basic maintenance on equipment from its most high-tech lines, such as Molecular Absorption Spectroscopy (UV-VIS), Fourier Transform Infrared Spectroscopy (FTIR), Gas Chromatography Coupled to Mass Spectrometry (GC-MS), High Performance Liquid Chromatography (HPLC), Analytical Thermogravimetry (TG) and Differential Scanning Calorimetry (DSC), by Tescan do Brasil in Scanning Electron Microscopy (SEM) and by Metrohm do Brasil in Ion Chromatography (IC) with emphasis on analysis in the sugar-energy sector.

    Dr. Ticiano Gomes do Nascimento

    Federal University of Alagoas (UFAL), Department of Pharmacy, Tabuleiro dos Martins Campus, CEP 57072-970, AL, Brazil.

    OrcID https://orcid.org/0000-0002-3856-8764

    graduated in Pharmacy from the Federal University of Paraíba (1998), master in Natural and Synthetic Bioactive Products from the Federal University of Paraíba (2000) and PhD in Natural and Synthetic Bioactive Products from the Federal University of Paraíba (2004). CNPq scholarship holder in Productivity, Technological Development and Innovative Extension level 2 - CA 82. Post-doc in purification and identification of secondary metabolites of red propolis from Alagoas using preparative HPLC and GC-MS and LC-Orbitrap-FTMS. Studies of fingerprinting, authenticity and seasonality of red propolis using metabolomics software (open Format) by the University of Strathclyde/Glasgow-UK. Associate Professor IV at the Federal University of Alagoas. He teaches Pharmacotechnics, Pharmaceutical Analysis, Quality Control of Drugs and Medications and Internship in Medications/Food. He was the coordinator of the Pharmacy course from June 2006 to March 2009. He is a Master's advisor for the Postgraduate Program in Pharmaceutical Sciences at UFAL, the Postgraduate Program in Nutrition at UFAL and for PROFNIT - Polo UFAL. He is currently a reviewer for the Brazilian Journal of Pharmacognosy, Brazilian Journal of Pharmaceutical Sciences, Journal of Thermal Analysis and Calorimetry, Journal of Chromatography B, Journal of Pharmaceutical and Biomedical Analysis and Food Chemistry. He has experience in Industrial Pharmacy, with emphasis on Development of Preformulated and Formulated Solids, and Semi-Solids, Study of Drug Stability and Bioequivalence (analytical stage); working mainly with the following analytical techniques: thermal analysis (DSC, DTA, Thermogravimetry), Infrared (Medium and NIR), Intrinsic Dissolution, Kinetics and Dissolution Profile and HPLC (HPLC-UV-DAD, HPLC-UV-MS-MS). He has been working on the development and validation of analytical methodologies and health products based on red propolis from Alagoas, greenish-brown propolis from União dos Palmares, green propolis from Minas Gerais, herbal medicines Guaco (Mikania glomerata), Chambá (Justicia pectoralis), Cat's claw (Uncaria tomentosa), tropical fruits Açaí (Euterpe oleraceae), native plants (Moringa oleifera) and synthetic medicines.

    Mr. Herbert Gonzaga Sousa

    Federal University of Piauí (UFPI), Department of Postgraduate Studies in Chemistry, Campus Ministro Petrônio Portella, Ininga, CEP 64049-550, PI, Brazil.

    OrcID https://orcid.org/0000-0001-8633-9918

    Graduated in Chemistry from the State University of Piauí- UESPI (2015.2). He has experience in Chemistry, with an emphasis on Organic Chemistry and Chemistry of Natural Products. During his undergraduate studies, he was a scholarship holder in the Tutorial Education Program (PET-UESPI), in the Institutional Program of Scholarships for Teaching Initiation (PIBID-UESPI) and a volunteer in the Institutional Program of Scholarships for Scientific Initiation (PIBIC-UESPI), working with natural products and medicinal plants from the Brazilian Northeast. He holds a master's degree in Chemistry, with a focus on Phytochemical Bioprospecting from the State University of Piauí- UESPI in 2018 (September). Currently, he is a PhD student in Chemistry at the Federal University of Piauí, integrating the Natural Products Laboratory (LPN-UFPI) and the Center for Applied Research in Sciences-NIAC. During my master's and doctorate, I acquired experience in plant phytochemistry (species of the Combretaceae family), using classical and modern techniques (analysis by classical chromatography and Liquid Chromatography coupled to Sequential Mass Spectrometry (LC-MS/MS)), Molecular Networking, Nuclear Magnetic Resonance (NMR).

    Dr. Gerardo Magela Vieira Junior

    Federal University of Piauí (UFPI), Department of Postgraduate Studies in Chemistry, Campus Ministro Petrônio Portella, Ininga, CEP 64049-550, PI, Brazil.

    OrcID https://orcid.org/0000-0001-8113-8957

    He holds a Bachelor's and Licentiate's Degree in Chemistry and a Master's Degree in Chemistry from the Federal University of Piauí (CAPES Concept 3 - 2005) and a PhD and Post-doctorate in Chemistry from the São Paulo State University (CAPES Concept 7 - 2010). He is currently an Associate Professor III at the Federal University of Piauí, Campus Ministro Petrônio Portela, Teresina and a CNPq Research Productivity Scholarship (PQ). He has experience in Chemistry, with an emphasis on Chemistry of Natural Products, working mainly on the following topics: chromatographic (HPLC and GC/MS) and spectrometric (UV, IR, NMR and MS) methods for isolation and identification of secondary (special) metabolites of plants and amphibians. Working with the plant genera Combretum, Couepia, Mimosa, Protium, Dipteryx and Casearia and with frogs of the genera Rhinella and Rhaebo, and in parallel in partnership with other research groups that carry out cytotoxic, anti-hypertensive, antifungal and antimalarial activities.

    Dr. Beneilde Cabral Moraes

    State University of Piauí (UESPI), Department of Postgraduate Studies in Chemistry, Torquato Neto Campus, 2231, Pirajá, CEP 64002-150 - PI, Brazil.

    OrcID https://orcid.org/0000-0003-3642-916X

    Graduated in Chemistry (Bachelor's and Bachelor's degrees) and Master's in Analytical Chemistry from the Federal University of Piauí (UFPI), PhD in Geography (in the area of ​​Physical Geography with studies in geochemistry and geomorphology of sedimentary deposits) from the Federal University of Pernambuco (UFPE). Adjunct Professor at the State University of Piauí (UESPI), Leader of the Interdisciplinary Center for Studies in Mineral Resources, Environment and Archaeometry - NIERMA and member of the Research Group in Chemical Education (GPEQUIM - UESPI). Has experience in Analytical Chemistry and Geochemistry, working especially on the themes: Archaeometry, Geochemistry of Archaeological Sediments, Mineral Characterization and Chemistry Teaching.

    Dr. Valdiléia Teixeira Uchôa

    State University of Piauí (UESPI), Department of Postgraduate Studies in Chemistry, Torquato Neto Campus, 2231, Pirajá, CEP 64002-150 - PI, Brazil.

    OrcID https://orcid.org/0000-0001-8080-6335

    She holds a degree in Chemistry from the Federal University of Piauí (2000), a Master's degree in Chemistry and Biotechnology (2004) and a PhD in Sciences: Chemistry and Biotechnology (2009) from the Federal University of Alagoas. Specialist in Higher Education Teaching - FSA (2008). Specialist in Food Quality Control (2013). She is currently an Associate Professor I of the Undergraduate and Postgraduate Program in Chemistry at the State University of Piauí - Department of Chemistry - CCN. Sub Coordinator of the Graduate Program in Chemistry. Coordinator and Professor of the Graduate Program in Biotechnology UECE / UESPI. Tutor of the PET-QUÍMICA-UESPI Program. She has experience in the area of ​​Chemistry, Biochemistry and Bromatology with an emphasis on Organic Chemistry and Natural Products, working mainly on the following topics: Teaching and Research in Chemistry, Phytochemistry, Food Analysis and Biochemistry.

Keywords

Abstract

Among the best-known medicinal plants in the world is Matricaria recutita L., popularly known as chamomile, which is related to the concept of calming, antispasmodic, anti-inflammatory, among others. Among the ways of using chamomile, consumption through teas predominates, medicinal plants are widely used, and to prevent side effects, this project experimentally evaluated, through physical exercises – classical chemicals, the quality and physical-chemical characteristics of plant extracts from the plant M. recutita, sold in natural product stores in the city of Teresina – Pi, verifying its suitability to the criteria of RDC nº 26 of 2014. The following were carried out: analysis of plant raw materials, labels and leaflets, production of extracts, colorimetric analysis , moisture content, foreign matter content and total ash content. All samples have been tested to comply with packaging standards in accordance with the current DRC. For colorimetric analysis, the samples indicated coordinates that agreed with each other. For analysis of moisture content, total ash, foreign bodies and pH, all samples are within expected levels. It is concluded that the chamomile samples meet the commercialization and production criteria determined by RDC nº 26 of 2014 of ANVISA

References

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Author(s)

  • Dr. Natasha Alves Rocha
    State University of Piauí (UESPI), Department of Postgraduate Studies in Chemistry, Torquato Neto Campus, 2231, Pirajá, CEP 64002-150 - PI, Brazil.
    https://orcid.org/0000-0003-1337-2885
  • Teacher Letícia Geovanna Cartonilho Siqueira
    State University of Piauí (UESPI), Department of Postgraduate Studies in Chemistry, Torquato Neto Campus, 2231, Pirajá, CEP 64002-150 - PI, Brazil.
    https://orcid.org/0000-0003-0603-4722
  • Mr. William da Silva Sousa
    State University of Piauí (UESPI), Department of Postgraduate Studies in Chemistry, Torquato Neto Campus, 2231, Pirajá, CEP 64002-150 - PI, Brazil.
    https://orcid.org/0000-0002-7652-3460
  • Dr. Girlene Soares de Figueirêdo
    Federal University of Piauí (UFPI), Department of Parasitology and Microbiology, Campus Ministro Petrônio Portella, Ininga, CEP 64049-550, PI, Brazil.
    https://orcid.org/0000-0002-6710-1549
  • Dr. Johnnatan Duarte de Freitas
    Federal Institute of Alagoas (IFAL), Department of Chemistry, Campus Centro, Centro, CEP 57020-600, AL, Brazil.
    https://orcid.org/0000-0002-6977-3322
  • Dr. Ticiano Gomes do Nascimento
    Federal University of Alagoas (UFAL), Department of Pharmacy, Tabuleiro dos Martins Campus, CEP 57072-970, AL, Brazil.
    https://orcid.org/0000-0002-3856-8764
  • Mr. Herbert Gonzaga Sousa
    Federal University of Piauí (UFPI), Department of Postgraduate Studies in Chemistry, Campus Ministro Petrônio Portella, Ininga, CEP 64049-550, PI, Brazil.
    https://orcid.org/0000-0001-8633-9918
  • Dr. Gerardo Magela Vieira Junior
    Federal University of Piauí (UFPI), Department of Postgraduate Studies in Chemistry, Campus Ministro Petrônio Portella, Ininga, CEP 64049-550, PI, Brazil.
    https://orcid.org/0000-0001-8113-8957
  • Dr. Beneilde Cabral Moraes
    State University of Piauí (UESPI), Department of Postgraduate Studies in Chemistry, Torquato Neto Campus, 2231, Pirajá, CEP 64002-150 - PI, Brazil.
    https://orcid.org/0000-0003-3642-916X
  • Dr. Valdiléia Teixeira Uchôa
    State University of Piauí (UESPI), Department of Postgraduate Studies in Chemistry, Torquato Neto Campus, 2231, Pirajá, CEP 64002-150 - PI, Brazil.
    https://orcid.org/0000-0001-8080-6335

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Characterization of the physicochemical profile, of Chamomile (Matricaria recutita L., Asteraceae) plant extracts. Rev Fitos [Internet]. 2025 Mar. 10 [cited 2025 Apr. 17];19:e1734. Available from: https://revistafitos.far.fiocruz.br/index.php/revista-fitos/article/view/1734
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