Analysis of the effectiveness of Calendula officinalis oil in injuries causedby pressure: a case report

Charlene Graef Hoffmann
OrcID
Mr. Cristiane de Pellegrin Kratz
OrcID

    Charlene Graef Hoffmann

    Integrated Regional University of Alto Uruguai and Missões, Santo Ângelo Campus, Department of Health Sciences, Rua Universidade das Missões, 464, University District, Zip Code 98802-470, Santo Ângelo, RS, Brazil.

    OrcID https://orcid.org/0009-0004-6906-5491

    Graduated in Pharmacy from the Regional Integrated University of Alto Uruguai and Missões (2024). Has experience in the Pharmacy area.

    Mr. Cristiane de Pellegrin Kratz

    Integrated Regional University of Alto Uruguai and Missões, Santo Ângelo Campus, Department of Health Sciences, Rua Universidade das Missões, 464, University District, Zip Code 98802-470, Santo Ângelo, RS, Brazil.

    OrcID https://orcid.org/0000-0003-1935-3191

    He holds a degree in PHARMACY from the Federal University of Santa Maria (1998), a degree in Industrial Pharmacy from the Federal University of Santa Maria (1999) and a master's degree in Pharmaceutical Sciences from the Federal University of Rio Grande do Sul (2002). He is currently a professor in the Department of Health Sciences at URI/Santo Ângelo Campus, RS, working in the Pharmacy Course in the areas of Pharmacotechnics and Cosmetology, in addition to participating in the Supervised Internship Committee. He has experience in managing higher education in the health area. He participates in the Institutional Committee for the Evaluation of Research Projects (CIAP), the Self-Assessment Committee (CPA) of the Campus and the Course. He carries out research and extension projects in the areas of Technological Development of Medicines and Cosmetics, Pharmaceutical Assistance and Health Education, being part of the Research Group in Pharmaceutical Sciences.

Keywords

Pressure ulcers
Calendula officinalis
Oil
Efficacy
Therapeutic uses

Abstract

Pressure ulcers are complex chronic wounds that negatively impact the patient's quality of life. Topical adjuvant therapy based on natural products and plants, such as Calendula officinalis oil, has been widely used to aid treatment. Thus, because the use of this plant is a common practice, including in domestic extractions, the objective of this work was to analyze the effectiveness of Calendula officinalis oil in a test formulation, for the treatment and prevention of pressure ulcer in bedridden patient. The research project was structured in two stages: production of the formulation followed by the application and clinical evaluation of the patient. The performance of the test formulation was analyzed during the study, using the National Pressure Ulcer Advisory Panel (NPUAP) scale and the Braden scale as evaluation instruments. The formulation produced proved to be viable. The results of its application in the patient demonstrated that the test formulation presented very similar results to the control (commercially available industrialized formulation). The formulation containing the essential oil of Calendula officinalis appears to be a safe and very promising therapy for the treatment of pressure ulcers.

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Author(s)

  • Charlene Graef Hoffmann
    Integrated Regional University of Alto Uruguai and Missões, Santo Ângelo Campus, Department of Health Sciences, Rua Universidade das Missões, 464, University District, Zip Code 98802-470, Santo Ângelo, RS, Brazil.
    https://orcid.org/0009-0004-6906-5491
  • Mr. Cristiane de Pellegrin Kratz
    Integrated Regional University of Alto Uruguai and Missões, Santo Ângelo Campus, Department of Health Sciences, Rua Universidade das Missões, 464, University District, Zip Code 98802-470, Santo Ângelo, RS, Brazil.
    https://orcid.org/0000-0003-1935-3191

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Analysis of the effectiveness of Calendula officinalis oil in injuries causedby pressure: a case report. Rev Fitos [Internet]. 2025 Mar. 31 [cited 2025 Dec. 7];19:e1746. Available from: https://revistafitos.far.fiocruz.br/index.php/revista-fitos/article/view/1746
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