Produtos Naturais Industrializáveis da Amazônia

B. Gilbert

doi:10.32712/2446-4775.2006.57

Produtos Naturais Industrializáveis da Amazônia

v. 2 n. 03 (2006)
30-38
16/10/2013
01/12/2006
https://doi.org/10.32712/2446-4775.2006.57

B. Gilbert

Palavras-chave

Produtos Naturais

Amazônia

Medicamentos Fitoterápicos

Óleos e Gorduras

Inseticidas

Repelentes de Insetos

Resumo

A Amazônia é freqüentemente citada como uma fonte de produtos naturais, cuja industrialização e venda no mercado mundial poderia trazer benefícios significantes à região. Neste trabalho alguns produtos específicos são apresentados nas classes de medicamentos, óleos e gorduras, inseticidas e repelentes de insetos. Outras classes como gomas, corantes, óleos essenciais e princípios amargos são abordados de maneira breve. Destaque é dado à importância de qualidade, quantidade, fornecimento regular e estabilidade de preço.

Referências

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BALICK, M.J.; GERSHOFF, S.N. Nutritional evaluation of the Jessenia bataua palm: source of high quality protein and oil from tropical America. Economic Botany, v.35, p.261-271, 1981.
BASILE, A.C.; SERTIE, J.A.; FREITAS, P.C.D.; ZANINE, A.C. Antiinflammatory activity of oleoresin from Brazilian Copaifera. Journal of Ethnopharmacology, v.22, n.1, p.101-109, 1988.
BERTANI, S.; HOUEL, E.; STIEN, D.; CHEVOLOT, L.; JULLIAN, V.; GARAVITO, G.; BOURDY, G.; DEHARO, E. Simalikalactone D is responsible for the antimalarial properties of an Amazonian traditional remedy made with Quassia amara L. (Simaroubaceae). Journal of Ethnopharmacology, v.108, n.1, p.155-157, 2006.
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BRANDÃO, M.G.; LACAILLE-DUBOIS, M.A.; TEIXEIRA, M.A.; WAGNER, H.A. Dammarane-type saponin from the roots of Ampelozizyphus amazonicus. Phytochemistry. v.34, n.4, p.1123-1126, 1993.
BRANDÃO, M.G.; KRETTLI, A.U.; SOARES, L.S.; NERY, C.G.; MARINUZZI, H.C. Antimalarial activity of extracts and fractions from Bidens pilosa and other Bidens species (Asteraceae) correlated with the presence of acetylene and flavonoid compounds. Journal of Ethnopharmacology, v.57, n.1, p.31-38, 1997.
CABRAL, J.A.; MCCHESNEY, J.D.; MILHOUS, W.K. A new antimalarial quassinoid from Simaba guianensis, Journal of Natural Products, v.56, n.11, p.1954-1961, 1993.
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DE MIRANDA, A.L.; SILVA, J.R.; REZENDE, C.M.; NEVES, J.S.; PARRINI, S.C.; PINHEIRO, M.L.; CORDEIRO, M.C.; TAMBORINI, E.; PINTO, A.C. Anti-inflammatory and analgesic activities of the latex containing triterpenes from Himatanthus sucuuba. Planta Medica, v.66, n.3, p.284-286, 2000.
EVANS, D.A.; RAJ, R.K. Larvicidal efficacy of quassin against Culex quinquefasciatus. Indian Journal of Medical Research, v.93, p.324-327, 1991.
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FERNANDES, R.M.; PEREIRA, N.A.; PAULO, L.G. Antiinflammatory activity of copaíba balsam (Copaifera cearensis Huber). Revista Brasileira de Farmácia, v.73, n.3, p.53-56, 1992.
FRANCOIS, G.; STEENACKERS, T.; ASSI, L.A.; STEGLICH, W.; LAMOTTKE, K.; HOLENZ, J.; BRINGMANN, G. Vismione H and structurally related anthranoid compounds of natural and synthetic origin as promising drugs against the human malaria parasite Plasmodium falciparum: structure-activity relationships. Parasitology Research, v.85, n.7, p.582-588, 1999.
FULLER, R.W.; WESTERGAARD, C.K.; COLLINS, J.W.; CARDELLINA, J.H. 2nd, BOYD, M.R.Vismiaphenones D-G, new prenylated benzophenones from Vismia cayennensis. Journal of Natural Products, v.62, n.1, p.67-69, 1999.
GOTTLIEB, O.R.; KOKETSU, M.; MAGALHÃES, M.T.; MAIA, J.G.S.; MENDES, A.I.R.; DA SILVA, M.L.; WILBERG, V.C. Óleos essenciais da Amazônia.VII. Acta Amazonica, v.11, n.1, p.143-148, 1981.
GURGEL, L.A.; SILVA, R.M.; SANTOS, F.A.; MARTINS, D.T.; MATTOS, P.O.; RAO, V.S. Studies on the antidiarrhoeal effect of dragon’s blood from Croton urucurana. Phytoterapy Research, v.15, n.4, p.319-322, 2001.
GURGEL, L.A.; SIDRIM, J.J.; MARTINS, D.T.; CECHINELFILHO, V.; RAO, V.S. In vitro antifungal activity of dragon’s blood from Croton urucurana against dermatophytes. Journal of Ethnopharmacology, v.97, n.2, p.409-412, 2005.
JONES, K. Review of sangre de drago (Croton lechleri) - a South American tree sap in the treatment of diarrhea, inflammation, insect bites, viral infections, and wounds: traditional uses to clinical research. Journal of Alternative and Complementary Medicine, v.9, n.6, p.877-896, 2003.
KARDONO, L.B.; TSAURI, S.; PADMAWINATA, K.; PEZZUTO, J.M.; KINGHORN, A.D. Cytotoxic constituents of the bark of Plumeria rubra collected in Indonesia. Journal of Natural Products, v.53, n.6, p.1447-1455, 1990.
KRETTLI, A.U.; ANDRADE-NETO, V.F.; BRANDÃO, M.G.; FERRARI, W.M.. The search for new antimalarial drugs from plants used to treat fever and malaria or plants randomly selected: a review. Memórias do Instituto Oswaldo Cruz, v.96, p.1033-1042, 2001.
LIMA-JUNIOR R.C.; OLIVEIRA, F.A.; GURGEL, F.A.; CAVALCANTE, I.J.; SANTOS, K.A.; CAMPOS, D.A.; VALE, C.A.; SILVA, R.M.; CHAVES, M.H.; RAO, V.S.; SANTOS, F.A. Attenuation of visceral nociception by alpha- and beta-amyrin, a triterpenoid mixture isolated from the resin of Protium heptaphyllum, in mice. Planta Medica, v.72, n.1, p.34-39, 2006.
NINCI, M.E. Prophylaxis and treatment of pediculosis with Quassia amara. Revista de la Facultad de Ciencias Medicas. Universidad Nacional de Cordoba, v.49, n.2, p.27-31, 1991.
OLIVEIRA, F.A.; LIMA-JUNIOR, R.C.; CORDEIRO, W.M.; VIEIRA-JUNIOR, G.M.; CHAVES, M.H.; ALMEIDA, F.R.; SILVA, R.M.; SANTOS, F.A.; RAO, V.S. Pentacyclic triterpenoids, alpha, beta-amyrins, suppress the scratching behavior in a mouse model of pruritus. Pharmacology Biochemistry & Behavior, v.78, n.4, p.719-725, 2004a.
OLIVEIRA, F.A; VIEIRA-JUNIOR, G.M.; CHAVES, M.H.; ALMEIDA, F.R.; FLORÃŠNCIO, M.G.; LIMA JR., R.C.; SILVA, R.M.; SANTOS, F.A.; RAO, V.S. Gastroprotective and antiinflammatory effects of resin from Protium heptaphyllum in mice and rats. Pharmacological Research, v.49, n.2, p.105-111, 2004b.
OLIVEIRA, F.Q.; ANDRADE-NETO, V.; KRETTLI, A.U.; BRANDÃO, M.G. New evidences of antimalarial activity of Bidens pilosa roots extract correlated with polyacetylenes and flavonoids. Journal of Ethnopharmacology, v.93, n.1, p.39-42, 2004c.
PAIVA, L.A.; ALENCAR-CUNHA, K.M.; SANTOS, F.A.; GRAMOSA, N.V.; SILVEIRA, E.R.; RAO, V.S. Investigation on the wound healing activity of oleo-resin from Copaifera langsdorffi in rats. Phytotherapy Research, v.16, n.8, p.737-739, 2002.
PENIDO, C.; COSTA, K.A.; COSTA, M.F.; PEREIRA, J.F.; SIANI, A.C.; HENRIQUES, M.G. Inhibition of allergen-induced eosinophil recruitment by natural tetranortriterpenoids is mediated by the suppression of IL-5, CCL11/eotaxin and NFkappaB activation. International Immunopharmacology, v.6, n.2, p. 109-121, 2006.
PENIDO, C.; COSTA, K.A.; PENNAFORTE, R.J.; COSTA, M.F.; PEREIRA, J.F., SIANI AC, HENRIQUES MG. Anti-allergic effects of natural tetranortriterpenoids isolated from Carapa guianensis Aublet on allergen-induced vascular permeability and hyperalgesia. Inflammation Research, v.54, n.7, p.295-303, 2005.
PERDUE, G.P.; BLOMSTER, R.N. South American plants III: Isolation of fulvoplumierin from Himatanthus sucuuba (M. Arg.) Woodson (Apocynaceae). Journal of Pharmaceutical Sciences, v.67, n.9, p.1322-1333, 1978.
PERES, M.T.; DELLE MONACHE, F.; CRUZ, A.B.; PIZZOLATTI, M.G.; YUNES, R.A. Chemical composition and antimicrobial activity of Croton urucurana Baillon (Euphorbiaceae). Journal of Ethnopharmacology, v.56, n.3, p.223-226, 1997.
PLOTKIN, M.J.; BALICK, M.J. Medicinal uses of South American palms. Journal of Ethnopharmacology, v.10. n.2, p.157-179, 1984.
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B. Gilbert
Departamento de Produtos Naturais, Instituto de Tecnologia em Fármacos, Fundação Oswaldo Cruz Rua Sizenando Nabuco 100, Manguinhos, 21041-250 Rio de Janeiro, RJ

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Produtos Naturais Industrializáveis da Amazônia. Rev Fitos [Internet]. 1º de dezembro de 2006 [citado 21º de novembro de 2024];2(03):30-8. Disponível em: https://revistafitos.far.fiocruz.br/index.php/revista-fitos/article/view/57

Este trabalho está licenciado sob uma licença Creative Commons Attribution 4.0 International License.

[1] ANDERSON, D.M.W.; DE PINTO, G.L. Studies of uronic acid materials. Part 71. Gum polysaccharides from three Parkia species. Phytochemistry, v.24, n.1, p.77-79, 1985.

[2] ANKRAH, N.A.; NYARKO, A.K.; ADDO, P.G.; OFOSUHENE, M.; DZOKOTO, C.; MARLEY, E.; ADDAE, M.M.; EKUBAN, F.A. Evaluation of efficacy and safety of a herbal medicine used for the treatment of malaria. Phytotherapy Research, v.17, n.6, p.697-701, 2003.

[3] BALICK, M.J.; GERSHOFF, S.N. Nutritional evaluation of the Jessenia bataua palm: source of high quality protein and oil from tropical America. Economic Botany, v.35, p.261-271, 1981.

[4] BASILE, A.C.; SERTIE, J.A.; FREITAS, P.C.D.; ZANINE, A.C. Antiinflammatory activity of oleoresin from Brazilian Copaifera. Journal of Ethnopharmacology, v.22, n.1, p.101-109, 1988.

[5] BERTANI, S.; HOUEL, E.; STIEN, D.; CHEVOLOT, L.; JULLIAN, V.; GARAVITO, G.; BOURDY, G.; DEHARO, E. Simalikalactone D is responsible for the antimalarial properties of an Amazonian traditional remedy made with Quassia amara L. (Simaroubaceae). Journal of Ethnopharmacology, v.108, n.1, p.155-157, 2006.

[6] BILL AND MELISSA GATES FOUNDATION. Facts Sheet: www.gatesfoundation.org/MediaCenter/FactSheet/default.htm; e outras fontes na Internet, 2006.

[7] BRANDÃO M.G.; LACAILLE-DUBOIS, M.A.; TEIXERA, M.A.; WAGNER, H. Triterpene saponins from the roots of Ampelozizyphus amazonicus. Phytochemistry. v.31, n.1, p.352-354, 1992.

[8] BRANDÃO, M.G.; LACAILLE-DUBOIS, M.A.; TEIXEIRA, M.A.; WAGNER, H.A. Dammarane-type saponin from the roots of Ampelozizyphus amazonicus. Phytochemistry. v.34, n.4, p.1123-1126, 1993.

[9] BRANDÃO, M.G.; KRETTLI, A.U.; SOARES, L.S.; NERY, C.G.; MARINUZZI, H.C. Antimalarial activity of extracts and fractions from Bidens pilosa and other Bidens species (Asteraceae) correlated with the presence of acetylene and flavonoid compounds. Journal of Ethnopharmacology, v.57, n.1, p.31-38, 1997.

[10] CABRAL, J.A.; MCCHESNEY, J.D.; MILHOUS, W.K. A new antimalarial quassinoid from Simaba guianensis, Journal of Natural Products, v.56, n.11, p.1954-1961, 1993.

[11] CARVALHO, J.C.; CASCON, V.; POSSEBON, L.S.; MORIMOTO, M.S.; CARDOSO, L.G.; KAPLAN, M.A.; GILBERT, B. Topical antiinflammatory and analgesic activities of Copaifera duckei Dwyer. Phytotherapy Research, v.19, n.11, p.946-950, 2005.

[12] DA SILVA, J.O.; COPPEDE, J.S.; FERNANDES, V.C.; SANT’ANA, C.D.; TICLI, F.K.; MAZZI, M.V.; GIGLIO, J.R.; PEREIRA, P.S.; SOARES, A.M.; SAMPAIO, S.V. Antihemorrhagic, antinucleolytic and other antiophidian properties of the aqueous extract from Pentaclethra macroloba. Journal of Ethnopharmacology, v.100, n.1-2, p.145-152, 2005.

[13] DE MIRANDA, A.L.; SILVA, J.R.; REZENDE, C.M.; NEVES, J.S.; PARRINI, S.C.; PINHEIRO, M.L.; CORDEIRO, M.C.; TAMBORINI, E.; PINTO, A.C. Anti-inflammatory and analgesic activities of the latex containing triterpenes from Himatanthus sucuuba. Planta Medica, v.66, n.3, p.284-286, 2000.

[14] EVANS, D.A.; RAJ, R.K. Larvicidal efficacy of quassin against Culex quinquefasciatus. Indian Journal of Medical Research, v.93, p.324-327, 1991.

[15] FAO: FOOD AND AGRICULTURE ORGANISATION. www.codexalimentarius.net. Publications; Guidelines for the Production, Processing, Labelling and Marketing of Organically Produced Foods. GL32-1999, Rev.1-2001, Annex 2. Permitted substances for the production of organic foods, Table 2. Substances for plant pest and disease control, p.43, 2005.

[16] FERNANDES, R.M.; PEREIRA, N.A.; PAULO, L.G. Antiinflammatory activity of copaíba balsam (Copaifera cearensis Huber). Revista Brasileira de Farmácia, v.73, n.3, p.53-56, 1992.

[17] FRANCOIS, G.; STEENACKERS, T.; ASSI, L.A.; STEGLICH, W.; LAMOTTKE, K.; HOLENZ, J.; BRINGMANN, G. Vismione H and structurally related anthranoid compounds of natural and synthetic origin as promising drugs against the human malaria parasite Plasmodium falciparum: structure-activity relationships. Parasitology Research, v.85, n.7, p.582-588, 1999.

[18] FULLER, R.W.; WESTERGAARD, C.K.; COLLINS, J.W.; CARDELLINA, J.H. 2nd, BOYD, M.R.Vismiaphenones D-G, new prenylated benzophenones from Vismia cayennensis. Journal of Natural Products, v.62, n.1, p.67-69, 1999.

[19] GOTTLIEB, O.R.; KOKETSU, M.; MAGALHÃES, M.T.; MAIA, J.G.S.; MENDES, A.I.R.; DA SILVA, M.L.; WILBERG, V.C. Óleos essenciais da Amazônia.VII. Acta Amazonica, v.11, n.1, p.143-148, 1981.

[20] GURGEL, L.A.; SILVA, R.M.; SANTOS, F.A.; MARTINS, D.T.; MATTOS, P.O.; RAO, V.S. Studies on the antidiarrhoeal effect of dragon’s blood from Croton urucurana. Phytoterapy Research, v.15, n.4, p.319-322, 2001.

[21] GURGEL, L.A.; SIDRIM, J.J.; MARTINS, D.T.; CECHINELFILHO, V.; RAO, V.S. In vitro antifungal activity of dragon’s blood from Croton urucurana against dermatophytes. Journal of Ethnopharmacology, v.97, n.2, p.409-412, 2005.

[22] JONES, K. Review of sangre de drago (Croton lechleri) - a South American tree sap in the treatment of diarrhea, inflammation, insect bites, viral infections, and wounds: traditional uses to clinical research. Journal of Alternative and Complementary Medicine, v.9, n.6, p.877-896, 2003.

[23] KARDONO, L.B.; TSAURI, S.; PADMAWINATA, K.; PEZZUTO, J.M.; KINGHORN, A.D. Cytotoxic constituents of the bark of Plumeria rubra collected in Indonesia. Journal of Natural Products, v.53, n.6, p.1447-1455, 1990.

[24] KRETTLI, A.U.; ANDRADE-NETO, V.F.; BRANDÃO, M.G.; FERRARI, W.M.. The search for new antimalarial drugs from plants used to treat fever and malaria or plants randomly selected: a review. Memórias do Instituto Oswaldo Cruz, v.96, p.1033-1042, 2001.

[25] LIMA-JUNIOR R.C.; OLIVEIRA, F.A.; GURGEL, F.A.; CAVALCANTE, I.J.; SANTOS, K.A.; CAMPOS, D.A.; VALE, C.A.; SILVA, R.M.; CHAVES, M.H.; RAO, V.S.; SANTOS, F.A. Attenuation of visceral nociception by alpha- and beta-amyrin, a triterpenoid mixture isolated from the resin of Protium heptaphyllum, in mice. Planta Medica, v.72, n.1, p.34-39, 2006.

[26] NINCI, M.E. Prophylaxis and treatment of pediculosis with Quassia amara. Revista de la Facultad de Ciencias Medicas. Universidad Nacional de Cordoba, v.49, n.2, p.27-31, 1991.

[27] OLIVEIRA, F.A.; LIMA-JUNIOR, R.C.; CORDEIRO, W.M.; VIEIRA-JUNIOR, G.M.; CHAVES, M.H.; ALMEIDA, F.R.; SILVA, R.M.; SANTOS, F.A.; RAO, V.S. Pentacyclic triterpenoids, alpha, beta-amyrins, suppress the scratching behavior in a mouse model of pruritus. Pharmacology Biochemistry & Behavior, v.78, n.4, p.719-725, 2004a.

[28] OLIVEIRA, F.A; VIEIRA-JUNIOR, G.M.; CHAVES, M.H.; ALMEIDA, F.R.; FLORÃŠNCIO, M.G.; LIMA JR., R.C.; SILVA, R.M.; SANTOS, F.A.; RAO, V.S. Gastroprotective and antiinflammatory effects of resin from Protium heptaphyllum in mice and rats. Pharmacological Research, v.49, n.2, p.105-111, 2004b.

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[30] PAIVA, L.A.; ALENCAR-CUNHA, K.M.; SANTOS, F.A.; GRAMOSA, N.V.; SILVEIRA, E.R.; RAO, V.S. Investigation on the wound healing activity of oleo-resin from Copaifera langsdorffi in rats. Phytotherapy Research, v.16, n.8, p.737-739, 2002.

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