Produtos Naturais Industrializáveis da Amazônia

B. Gilbert

doi:10.32712/2446-4775.2006.57

Industrializable Natural Products from the Amazon

Vol. 2 No. 03 (2006)
30-38
16/10/2013
01/12/2006
https://doi.org/10.32712/2446-4775.2006.57

B. Gilbert

Keywords

Abstract

The Amazon basin, as has been frequently recognized has an abundance of natural resources that could enter the world market with considerable economic benefit to the region. The present survey describes what products these are with some indications of specific medicinal products, fats and oils, insecticides and repellents. Other classes such as gums, dyes, essential oils and bitter principles are touched on. The importance of quality, quantity, regularity of supply and of price is emphasized.

References

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BRANDÃO, M.G.; LACAILLE-DUBOIS, M.A.; TEIXEIRA, M.A.; WAGNER, H.A. Dammarane-type saponin from the roots of Ampelozizyphus amazonicus. Phytochemistry. v.34, n.4, p.1123-1126, 1993.
BRANDÃO, M.G.; KRETTLI, A.U.; SOARES, L.S.; NERY, C.G.; MARINUZZI, H.C. Antimalarial activity of extracts and fractions from Bidens pilosa and other Bidens species (Asteraceae) correlated with the presence of acetylene and flavonoid compounds. Journal of Ethnopharmacology, v.57, n.1, p.31-38, 1997.
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FERNANDES, R.M.; PEREIRA, N.A.; PAULO, L.G. Antiinflammatory activity of copaíba balsam (Copaifera cearensis Huber). Revista Brasileira de Farmácia, v.73, n.3, p.53-56, 1992.
FRANCOIS, G.; STEENACKERS, T.; ASSI, L.A.; STEGLICH, W.; LAMOTTKE, K.; HOLENZ, J.; BRINGMANN, G. Vismione H and structurally related anthranoid compounds of natural and synthetic origin as promising drugs against the human malaria parasite Plasmodium falciparum: structure-activity relationships. Parasitology Research, v.85, n.7, p.582-588, 1999.
FULLER, R.W.; WESTERGAARD, C.K.; COLLINS, J.W.; CARDELLINA, J.H. 2nd, BOYD, M.R.Vismiaphenones D-G, new prenylated benzophenones from Vismia cayennensis. Journal of Natural Products, v.62, n.1, p.67-69, 1999.
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GURGEL, L.A.; SILVA, R.M.; SANTOS, F.A.; MARTINS, D.T.; MATTOS, P.O.; RAO, V.S. Studies on the antidiarrhoeal effect of dragon’s blood from Croton urucurana. Phytoterapy Research, v.15, n.4, p.319-322, 2001.
GURGEL, L.A.; SIDRIM, J.J.; MARTINS, D.T.; CECHINELFILHO, V.; RAO, V.S. In vitro antifungal activity of dragon’s blood from Croton urucurana against dermatophytes. Journal of Ethnopharmacology, v.97, n.2, p.409-412, 2005.
JONES, K. Review of sangre de drago (Croton lechleri) - a South American tree sap in the treatment of diarrhea, inflammation, insect bites, viral infections, and wounds: traditional uses to clinical research. Journal of Alternative and Complementary Medicine, v.9, n.6, p.877-896, 2003.
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LIMA-JUNIOR R.C.; OLIVEIRA, F.A.; GURGEL, F.A.; CAVALCANTE, I.J.; SANTOS, K.A.; CAMPOS, D.A.; VALE, C.A.; SILVA, R.M.; CHAVES, M.H.; RAO, V.S.; SANTOS, F.A. Attenuation of visceral nociception by alpha- and beta-amyrin, a triterpenoid mixture isolated from the resin of Protium heptaphyllum, in mice. Planta Medica, v.72, n.1, p.34-39, 2006.
NINCI, M.E. Prophylaxis and treatment of pediculosis with Quassia amara. Revista de la Facultad de Ciencias Medicas. Universidad Nacional de Cordoba, v.49, n.2, p.27-31, 1991.
OLIVEIRA, F.A.; LIMA-JUNIOR, R.C.; CORDEIRO, W.M.; VIEIRA-JUNIOR, G.M.; CHAVES, M.H.; ALMEIDA, F.R.; SILVA, R.M.; SANTOS, F.A.; RAO, V.S. Pentacyclic triterpenoids, alpha, beta-amyrins, suppress the scratching behavior in a mouse model of pruritus. Pharmacology Biochemistry & Behavior, v.78, n.4, p.719-725, 2004a.
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OLIVEIRA, F.Q.; ANDRADE-NETO, V.; KRETTLI, A.U.; BRANDÃO, M.G. New evidences of antimalarial activity of Bidens pilosa roots extract correlated with polyacetylenes and flavonoids. Journal of Ethnopharmacology, v.93, n.1, p.39-42, 2004c.
PAIVA, L.A.; ALENCAR-CUNHA, K.M.; SANTOS, F.A.; GRAMOSA, N.V.; SILVEIRA, E.R.; RAO, V.S. Investigation on the wound healing activity of oleo-resin from Copaifera langsdorffi in rats. Phytotherapy Research, v.16, n.8, p.737-739, 2002.
PENIDO, C.; COSTA, K.A.; COSTA, M.F.; PEREIRA, J.F.; SIANI, A.C.; HENRIQUES, M.G. Inhibition of allergen-induced eosinophil recruitment by natural tetranortriterpenoids is mediated by the suppression of IL-5, CCL11/eotaxin and NFkappaB activation. International Immunopharmacology, v.6, n.2, p. 109-121, 2006.
PENIDO, C.; COSTA, K.A.; PENNAFORTE, R.J.; COSTA, M.F.; PEREIRA, J.F., SIANI AC, HENRIQUES MG. Anti-allergic effects of natural tetranortriterpenoids isolated from Carapa guianensis Aublet on allergen-induced vascular permeability and hyperalgesia. Inflammation Research, v.54, n.7, p.295-303, 2005.
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B. Gilbert
Departamento de Produtos Naturais, Instituto de Tecnologia em Fármacos, Fundação Oswaldo Cruz Rua Sizenando Nabuco 100, Manguinhos, 21041-250 Rio de Janeiro, RJ

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Industrializable Natural Products from the Amazon. Rev Fitos [Internet]. 2006 Dec. 1 [cited 2024 Nov. 22];2(03):30-8. Available from: https://revistafitos.far.fiocruz.br/index.php/revista-fitos/article/view/57

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[1] ANDERSON, D.M.W.; DE PINTO, G.L. Studies of uronic acid materials. Part 71. Gum polysaccharides from three Parkia species. Phytochemistry, v.24, n.1, p.77-79, 1985.

[2] ANKRAH, N.A.; NYARKO, A.K.; ADDO, P.G.; OFOSUHENE, M.; DZOKOTO, C.; MARLEY, E.; ADDAE, M.M.; EKUBAN, F.A. Evaluation of efficacy and safety of a herbal medicine used for the treatment of malaria. Phytotherapy Research, v.17, n.6, p.697-701, 2003.

[3] BALICK, M.J.; GERSHOFF, S.N. Nutritional evaluation of the Jessenia bataua palm: source of high quality protein and oil from tropical America. Economic Botany, v.35, p.261-271, 1981.

[4] BASILE, A.C.; SERTIE, J.A.; FREITAS, P.C.D.; ZANINE, A.C. Antiinflammatory activity of oleoresin from Brazilian Copaifera. Journal of Ethnopharmacology, v.22, n.1, p.101-109, 1988.

[5] BERTANI, S.; HOUEL, E.; STIEN, D.; CHEVOLOT, L.; JULLIAN, V.; GARAVITO, G.; BOURDY, G.; DEHARO, E. Simalikalactone D is responsible for the antimalarial properties of an Amazonian traditional remedy made with Quassia amara L. (Simaroubaceae). Journal of Ethnopharmacology, v.108, n.1, p.155-157, 2006.

[6] BILL AND MELISSA GATES FOUNDATION. Facts Sheet: www.gatesfoundation.org/MediaCenter/FactSheet/default.htm; e outras fontes na Internet, 2006.

[7] BRANDÃO M.G.; LACAILLE-DUBOIS, M.A.; TEIXERA, M.A.; WAGNER, H. Triterpene saponins from the roots of Ampelozizyphus amazonicus. Phytochemistry. v.31, n.1, p.352-354, 1992.

[8] BRANDÃO, M.G.; LACAILLE-DUBOIS, M.A.; TEIXEIRA, M.A.; WAGNER, H.A. Dammarane-type saponin from the roots of Ampelozizyphus amazonicus. Phytochemistry. v.34, n.4, p.1123-1126, 1993.

[9] BRANDÃO, M.G.; KRETTLI, A.U.; SOARES, L.S.; NERY, C.G.; MARINUZZI, H.C. Antimalarial activity of extracts and fractions from Bidens pilosa and other Bidens species (Asteraceae) correlated with the presence of acetylene and flavonoid compounds. Journal of Ethnopharmacology, v.57, n.1, p.31-38, 1997.

[10] CABRAL, J.A.; MCCHESNEY, J.D.; MILHOUS, W.K. A new antimalarial quassinoid from Simaba guianensis, Journal of Natural Products, v.56, n.11, p.1954-1961, 1993.

[11] CARVALHO, J.C.; CASCON, V.; POSSEBON, L.S.; MORIMOTO, M.S.; CARDOSO, L.G.; KAPLAN, M.A.; GILBERT, B. Topical antiinflammatory and analgesic activities of Copaifera duckei Dwyer. Phytotherapy Research, v.19, n.11, p.946-950, 2005.

[12] DA SILVA, J.O.; COPPEDE, J.S.; FERNANDES, V.C.; SANT’ANA, C.D.; TICLI, F.K.; MAZZI, M.V.; GIGLIO, J.R.; PEREIRA, P.S.; SOARES, A.M.; SAMPAIO, S.V. Antihemorrhagic, antinucleolytic and other antiophidian properties of the aqueous extract from Pentaclethra macroloba. Journal of Ethnopharmacology, v.100, n.1-2, p.145-152, 2005.

[13] DE MIRANDA, A.L.; SILVA, J.R.; REZENDE, C.M.; NEVES, J.S.; PARRINI, S.C.; PINHEIRO, M.L.; CORDEIRO, M.C.; TAMBORINI, E.; PINTO, A.C. Anti-inflammatory and analgesic activities of the latex containing triterpenes from Himatanthus sucuuba. Planta Medica, v.66, n.3, p.284-286, 2000.

[14] EVANS, D.A.; RAJ, R.K. Larvicidal efficacy of quassin against Culex quinquefasciatus. Indian Journal of Medical Research, v.93, p.324-327, 1991.

[15] FAO: FOOD AND AGRICULTURE ORGANISATION. www.codexalimentarius.net. Publications; Guidelines for the Production, Processing, Labelling and Marketing of Organically Produced Foods. GL32-1999, Rev.1-2001, Annex 2. Permitted substances for the production of organic foods, Table 2. Substances for plant pest and disease control, p.43, 2005.

[16] FERNANDES, R.M.; PEREIRA, N.A.; PAULO, L.G. Antiinflammatory activity of copaíba balsam (Copaifera cearensis Huber). Revista Brasileira de Farmácia, v.73, n.3, p.53-56, 1992.

[17] FRANCOIS, G.; STEENACKERS, T.; ASSI, L.A.; STEGLICH, W.; LAMOTTKE, K.; HOLENZ, J.; BRINGMANN, G. Vismione H and structurally related anthranoid compounds of natural and synthetic origin as promising drugs against the human malaria parasite Plasmodium falciparum: structure-activity relationships. Parasitology Research, v.85, n.7, p.582-588, 1999.

[18] FULLER, R.W.; WESTERGAARD, C.K.; COLLINS, J.W.; CARDELLINA, J.H. 2nd, BOYD, M.R.Vismiaphenones D-G, new prenylated benzophenones from Vismia cayennensis. Journal of Natural Products, v.62, n.1, p.67-69, 1999.

[19] GOTTLIEB, O.R.; KOKETSU, M.; MAGALHÃES, M.T.; MAIA, J.G.S.; MENDES, A.I.R.; DA SILVA, M.L.; WILBERG, V.C. Óleos essenciais da Amazônia.VII. Acta Amazonica, v.11, n.1, p.143-148, 1981.

[20] GURGEL, L.A.; SILVA, R.M.; SANTOS, F.A.; MARTINS, D.T.; MATTOS, P.O.; RAO, V.S. Studies on the antidiarrhoeal effect of dragon’s blood from Croton urucurana. Phytoterapy Research, v.15, n.4, p.319-322, 2001.

[21] GURGEL, L.A.; SIDRIM, J.J.; MARTINS, D.T.; CECHINELFILHO, V.; RAO, V.S. In vitro antifungal activity of dragon’s blood from Croton urucurana against dermatophytes. Journal of Ethnopharmacology, v.97, n.2, p.409-412, 2005.

[22] JONES, K. Review of sangre de drago (Croton lechleri) - a South American tree sap in the treatment of diarrhea, inflammation, insect bites, viral infections, and wounds: traditional uses to clinical research. Journal of Alternative and Complementary Medicine, v.9, n.6, p.877-896, 2003.

[23] KARDONO, L.B.; TSAURI, S.; PADMAWINATA, K.; PEZZUTO, J.M.; KINGHORN, A.D. Cytotoxic constituents of the bark of Plumeria rubra collected in Indonesia. Journal of Natural Products, v.53, n.6, p.1447-1455, 1990.

[24] KRETTLI, A.U.; ANDRADE-NETO, V.F.; BRANDÃO, M.G.; FERRARI, W.M.. The search for new antimalarial drugs from plants used to treat fever and malaria or plants randomly selected: a review. Memórias do Instituto Oswaldo Cruz, v.96, p.1033-1042, 2001.

[25] LIMA-JUNIOR R.C.; OLIVEIRA, F.A.; GURGEL, F.A.; CAVALCANTE, I.J.; SANTOS, K.A.; CAMPOS, D.A.; VALE, C.A.; SILVA, R.M.; CHAVES, M.H.; RAO, V.S.; SANTOS, F.A. Attenuation of visceral nociception by alpha- and beta-amyrin, a triterpenoid mixture isolated from the resin of Protium heptaphyllum, in mice. Planta Medica, v.72, n.1, p.34-39, 2006.

[26] NINCI, M.E. Prophylaxis and treatment of pediculosis with Quassia amara. Revista de la Facultad de Ciencias Medicas. Universidad Nacional de Cordoba, v.49, n.2, p.27-31, 1991.

[27] OLIVEIRA, F.A.; LIMA-JUNIOR, R.C.; CORDEIRO, W.M.; VIEIRA-JUNIOR, G.M.; CHAVES, M.H.; ALMEIDA, F.R.; SILVA, R.M.; SANTOS, F.A.; RAO, V.S. Pentacyclic triterpenoids, alpha, beta-amyrins, suppress the scratching behavior in a mouse model of pruritus. Pharmacology Biochemistry & Behavior, v.78, n.4, p.719-725, 2004a.

[28] OLIVEIRA, F.A; VIEIRA-JUNIOR, G.M.; CHAVES, M.H.; ALMEIDA, F.R.; FLORÃŠNCIO, M.G.; LIMA JR., R.C.; SILVA, R.M.; SANTOS, F.A.; RAO, V.S. Gastroprotective and antiinflammatory effects of resin from Protium heptaphyllum in mice and rats. Pharmacological Research, v.49, n.2, p.105-111, 2004b.

[29] OLIVEIRA, F.Q.; ANDRADE-NETO, V.; KRETTLI, A.U.; BRANDÃO, M.G. New evidences of antimalarial activity of Bidens pilosa roots extract correlated with polyacetylenes and flavonoids. Journal of Ethnopharmacology, v.93, n.1, p.39-42, 2004c.

[30] PAIVA, L.A.; ALENCAR-CUNHA, K.M.; SANTOS, F.A.; GRAMOSA, N.V.; SILVEIRA, E.R.; RAO, V.S. Investigation on the wound healing activity of oleo-resin from Copaifera langsdorffi in rats. Phytotherapy Research, v.16, n.8, p.737-739, 2002.

[31] PENIDO, C.; COSTA, K.A.; COSTA, M.F.; PEREIRA, J.F.; SIANI, A.C.; HENRIQUES, M.G. Inhibition of allergen-induced eosinophil recruitment by natural tetranortriterpenoids is mediated by the suppression of IL-5, CCL11/eotaxin and NFkappaB activation. International Immunopharmacology, v.6, n.2, p. 109-121, 2006.

[32] PENIDO, C.; COSTA, K.A.; PENNAFORTE, R.J.; COSTA, M.F.; PEREIRA, J.F., SIANI AC, HENRIQUES MG. Anti-allergic effects of natural tetranortriterpenoids isolated from Carapa guianensis Aublet on allergen-induced vascular permeability and hyperalgesia. Inflammation Research, v.54, n.7, p.295-303, 2005.

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