Phytochemical study of Plumbago auriculata Lam
Abstract
The family Plumbaginaceae is formed by herbs, shrubs or subshrubs with cosmopolitan distribution. Its metabolic production is characterized by the presence of naphthoquinones, flavonoids, terpenoids and steroids, the formers being considered the chemosystematic markers for the group. The genus Plumbago, comprises approximately 10 species, and has already shown some chemical and pharmacological studies. Phytochemical studies of P. auriculata resulted on the isolation of sitosterol, stigmasterol; 3-O-glycosylsistosterol, palmitic acid; plumbagic acid, epi-isoshinanolone, plumbagin, and a mixture of two flavonoids (luteolin and 5-methoxyluteolin). Although these compounds have been previously reported in literature, this is the first report of the isolation of luteolin and 5-methoxyluteolin in P. auriculata.
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Author(s)
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S. R. De Paiva
Setor Botânica, Departamento de Biologia Geral, Universidade Federal Fluminense, C. P. 100.436, 24001-970, Niterói, RJ, Brasil Laboratório de Química de Produtos Naturais, Far-Manguinhos, Fundação Oswaldo Cruz Rio de Janeiro, RJ
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M. R. Figueiredo
Laboratório de Química de Produtos Naturais, Far-Manguinhos, Fundação Oswaldo Cruz Rio de Janeiro, RJ
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M. A. C. Kaplan
Núcleo de Pesquisas de Produtos Naturais, Universidade Federal do Rio de Janeiro, RJ.
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